LLGL2

Gene Symbol LLGL2
Entrez Gene 3993
Alt Symbol HGL, Hugl-2, LGL2
Species Human
Gene Type protein-coding
Description lethal giant larvae homolog 2 (Drosophila)
Other Description human giant larvae homolog|lethal(2) giant larvae protein homolog 2
Swissprots Q6P1M3 Q14521 Q9BR62
Accessions EAW89280 EAW89281 EAW89282 EAW89283 Q6P1M3 AK025401 AK125563 AK126687 BAG54359 AK301204 BAG62781 AK315126 BC006503 AAH06503 BC010879 AAH10879 BC031842 AAH31842 BC064994 AAH64994 BC067840 X87342 CAA60780 XM_006721897 XP_006721960 XM_011524801 XP_011523103 XM_011524802 XP_011523104 XM_011524803 XP_011523105 XM_011524804 XP_011523106 XM_011524805 XP_011523107 XM_011524806 XP_011523108 XM_011524807 XP_011523109 NM_001015002 NP_001015002 NM_001031803 NP_001026973 NM_004524 NP_004515
Function Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. {ECO:0000269|PubMed:15632202}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15632202}. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
Top Pathways Tight junction, Hippo signaling pathway

LLGL2 (H-58) - sc-135289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LLGL2 (H-58): sc-135289. Western blot analysis of LLGL2 expression in ES-2 (A) and K-562 (B) whole cell lysates.

LLGL2 (T-13) - sc-164884 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LLGL2 (A-4) - sc-376857 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LLGL2 (A-4): sc-376857. Western blot analysis of LLGL2 expression in K-562 whole cell lysate.

LLGL2 (E-15) - sc-164882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LLGL2 (G-15) - sc-164883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LLGL2 (I-13) - sc-101242 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
LLGL2 (I-13): sc-101242. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human salivary gland tissue showing membrane and cytoplasmic localization.

Anti-LLGL2 antibody - ab55423 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
LLGL2 antibody (ab55423) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human salivary gland.

Anti-LLGL2 antibody - ab73304 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LLGL2 antibody - ab94928 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-LLGL2 antibody (ab94928) at 1/50 dilution + K562 cell line lysate at 35 µg

Anti-LLGL2 antibody - Aminoterminal end - ab71469 from Abcam

Prices $313.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LLGL2 antibody - Aminoterminal end (ab71469) at 1/20 dilution + 293 cell line lysate at 35 µg

Anti-LLGL2 Antibody (N-Terminus) - LS-C153477 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LLGL2 Antibody - LS-C308769 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LLGL2 Antibody - LS-C310887 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LLGL2 Antibody (N-Terminus) - LS-C144834 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LLGL2 Antibody (aa940-973) - LS-C99646 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of LLGL2 antibody in K562 cell line lysates (35 ug/lane). LLGL2 (arrow) was detected using the purified antibody.

Anti-LLGL2 Antibody (aa165-199) - LS-C99647 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-LLGL2 Pabin 293 cell line lysate (35 ug/lane). LLGL2(arrow) was detected using the purified antibody.

Anti-LLGL2 Antibody (clone 4G2) - LS-C104985 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G2
Western blot of LLGL2 expression in transfected 293T cell line by LLGL2 monoclonal antibody (M06), clone 4G2.

LLGL2 Antibody (4G2) - H00003993-M06 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G2
Western Blot: LLGL2 Antibody (4G2) [H00003993-M06] - Analysis of LLGL2 expression in transfected 293T cell line by LLGL2 monoclonal antibody (M06), clone 4G2. Lane 1: LLGL2 transfected lysatE (113 KDa). Lane 2: Non-transfected lysate.

LLGL2 Antibody - NBP1-81753 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: LLGL2 Antibody [NBP1-81753] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

LLGL2 Antibody - H00003993-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

LLGL2 Antibody - H00003993-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: LLGL2 Antibody [H00003993-D01P] - Analysis of LLGL2 expression in transfected 293T cell line by LLGL2 polyclonal antibody.Lane 1: LLGL2 transfected lysate(113.40 KDa).Lane 2: Non-transfected lysate.

LLGL2 Antibody - NBP2-17151 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

LLGL2 Antibody - H00003993-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

LLGL2 Antibody - H00003993-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LLGL2 Polyclonal Antibody - bs-4771R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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