LLGL2

Gene Symbol LLGL2
Entrez Gene 3993
Alt Symbol HGL, Hugl-2, LGL2
Species Human
Gene Type protein-coding
Description lethal giant larvae homolog 2 (Drosophila)
Other Description human giant larvae homolog|lethal(2) giant larvae protein homolog 2
Swissprots Q6P1M3 Q14521 Q9BR62
Accessions EAW89280 EAW89281 EAW89282 EAW89283 Q6P1M3 AK025401 AK125563 AK126687 BAG54359 AK301204 BAG62781 AK315126 BC006503 AAH06503 BC010879 AAH10879 BC031842 AAH31842 BC064994 AAH64994 BC067840 X87342 CAA60780 XM_006721897 XP_006721960 XM_011524801 XP_011523103 XM_011524802 XP_011523104 XM_011524803 XP_011523105 XM_011524804 XP_011523106 XM_011524805 XP_011523107 XM_011524806 XP_011523108 XM_011524807 XP_011523109 NM_001015002 NP_001015002 NM_001031803 NP_001026973 NM_004524 NP_004515
Function Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. {ECO:0000269|PubMed:15632202}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15632202}. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
Top Pathways Tight junction, Hippo signaling pathway

Human LLGL2 cDNA clone(NM_001015002.1) - CDFH010446 from Creative Biomart

Species Human
Accession NM_001015002.1

Human LLGL2 cDNA clone(NM_001031803.1) - CDFH010447 from Creative Biomart

Species Human
Accession NM_001031803.1

Human LLGL2 cDNA clone(NM_004524.2) - CDFH010448 from Creative Biomart

Species Human
Accession NM_004524.2

Human LLGL2 ORF Clone(NM_004524.2) - CDCR288268 from Creative Biomart

Species Human
Accession NM_004524.2

Human LLGL2 ORF Clone(NM_004524.2) - CDCR288269 from Creative Biomart

Species Human
Accession NM_004524.2

Human LLGL2 ORF Clone(NM_001015002.1) - CDCR341676 from Creative Biomart

Species Human
Accession NM_001015002.1

Human LLGL2 ORF Clone(NM_001015002.1) - CDCR341677 from Creative Biomart

Species Human
Accession NM_001015002.1

Human LLGL2 ORF Clone(NM_001031803.1) - CDCR342902 from Creative Biomart

Species Human
Accession NM_001031803.1

Human LLGL2 ORF Clone(NM_001031803.1) - CDCR342903 from Creative Biomart

Species Human
Accession NM_001031803.1

Human LLGL2 ORF clone(NM_004524.2) - CDCR008837 from Creative Biomart

Species Human
Accession NM_004524.2

Human LLGL2 ORF Clone(NM_001015002.1) - CDCL168732 from Creative Biomart

Species Human
Accession NM_001015002.1

Human LLGL2 ORF Clone(NM_004524.2) - CDCR288268 from Creative biogene

Species Human

Human LLGL2 ORF Clone(NM_001015002.1) - CDCR341676 from Creative biogene

Species Human

Human LLGL2 ORF clone (NM_001015002.1) - CDCL127587 from Creative biogene

Species Human

Human LLGL2 ORF clone (NM_001031803.1) - CDCL127589 from Creative biogene

Species Human

Human LLGL2 cDNA Clone(NM_001015002.1) - CDFH010446 from Creative biogene

Species Human

Human LLGL2 cDNA Clone(NM_001031803.1) - CDFH010447 from Creative biogene

Species Human

Human LLGL2 cDNA Clone(NM_004524.2) - CDFH010448 from Creative biogene

Species Human
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