LILRA3

Gene Symbol LILRA3
Entrez Gene 11026
Alt Symbol CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4
Species Human
Gene Type protein-coding
Description leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Other Description CD85 antigen-like family member E|immunoglobulin-like transcript 6|leukocyte immunoglobulin-like receptor 4|leukocyte immunoglobulin-like receptor A3|leukocyte immunoglobulin-like receptor subfamily A member 3|monocyte inhibitory receptor HM43/HM31
Swissprots Q8N6C8 Q8N151 Q8NHJ3 Q8NHJ1 Q8NHJ2 Q8N154 J3KPM2 O15469 O75016 Q8NHJ4 O15470
Accessions AAK58867 AAM18035 AAM18036 AAM18037 AAM18038 AAM18039 AAM18040 AAM18041 AAM18042 CCF76528 CCF76529 EAW72225 Q8N6C8 AF014923 AAC51885 AF014924 AAC51886 AF025527 AAB87661 AI655471 BC028208 AAH28208 BX280714 DQ891075 ABM82001 DQ894258 ABM85184 U91926 AAB68666 U91927 AAB68667 XM_005277092 XP_005277149 XM_011547082 XP_011545384 XM_011547083 XP_011545385 XM_011547084 XP_011545386 XM_011547085 XP_011545387 XM_011547086 XP_011545388 XM_011547087 XP_011545389 XM_011547088 XP_011545390 XM_011547503 XP_011545805 XM_011547504 XP_011545806 XM_011547505 XP_011545807 XM_011547506 XP_011545808 XM_011547507 XP_011545809 XM_011548673 XP_011546975 XM_011548674 XP_011546976 XM_011548675 XP_011546977 XM_011548676 XP_011546978 XM_011548677 XP_011546979 NM_001172654 NP_001166125 NM_006865 NP_006856
Function Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes. {ECO:0000269|PubMed:21559424, ECO:0000269|PubMed:24085305}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung. {ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}.
Top Pathways Osteoclast differentiation

Anti-LILRA 2 + 3 antibody - ab190601 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LILRA 2 + 3 antibody (ab190601) at 1/500 dilution + extracts from MCF7 cells at 30 µg

Anti-LILRA3 antibody - ab56827 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56827 LILRA3 antibody at 1ug/ml.

Anti-LILRA3 antibody - ab111562 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-LILRA3 antibody (ab111562) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

Anti-LILRA3 antibody - ab131013 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-LILRA3 antibody (ab131013) at 1 µg/ml + Human fetal kidney lysate at 10 µg

Anti-LILRA3 antibody - ab172647 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-LILRA3 antibody (ab172647) at 1 µg/mlLane 1 : LILRA3-transfected 293T cell line lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-LILRA3 antibody - C-terminal - ab180230 from Abcam

Prices $357.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LILRA3 antibody - C-terminal (ab180230) at 1/1000 dilutionLane 1 : Daudi cell line lysateLane 2 : HL60 cell line lysateLane 3 : Raji cell line lysateLane 4 : Ramos cell line lysateLysates/proteins at 35 µg per lane.

Anti-LILRA3 Antibody (APC) - LS-C182899 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-LILRA3 / CD85e Antibody (aa219-438, Biotin) - LS-C297985 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LILRA3 / CD85e Antibody - LS-C308749 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-LILRA3 / CD85e Antibody (aa219-438, FITC) - LS-C305341 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LILRA3 / CD85e Antibody - LS-C308751 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LILRA3 / CD85e Antibody - LS-C310873 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LILRA3 / CD85e Antibody (aa362-411) - LS-C151952 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LILRA3 antibody Western Blot of Human Kidney.

Anti-LILRA3 / CD85e Antibody (C-Terminus) - LS-C151951 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LILRA3 antibody Western Blot of OVCAR-3.

Anti-LILRA3 / CD85e Antibody (aa219-438) - LS-C295150 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant LILRA3.

Anti-LILRA3 / CD85e Antibody (aa350-378) - LS-C203990 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LILRA3 Antibody western blot of Daudi,HL-60,Raji and Ramos cell line lysates (35 ug/lane). The LILRA3 antibody detected the LILRA3 protein (arrow).

ILT6/CD85e/LILRA3 Antibody (293106) - MAB2574 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 293106

ILT6/CD85e/LILRA3 Antibody [Unconjugated] - AF2574 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Human peripheral blood monoctyes were stained with Mouse Anti-Human CD14 APC‑conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Goat Anti-Human LILRA3/CD85e Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2574) or (B) Normal Goat IgG Control(Catalog # AB-108-C) followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

ILT6/CD85e/LILRA3 Antibody (2E9) - H00011026-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E9
Western Blot: ILT6/CD85e/LILRA3 Antibody (2E9) [H00011026-M01] - Analysis of LILRA3 expression in transfected 293T cell line by LILRA3 monoclonal antibody (M01), clone 2E9.Lane 1: LILRA3 transfected lysate(50.485 KDa).Lane 2: Non-transfected lysate.

ILT6/CD85e/LILRA3 Antibody - NBP2-19351 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ILT6/CD85e/LILRA3 Antibody [NBP2-19351] - Sample (30 ug of whole cell lysate) A: HCT116 10% SDS PAGE gel, diluted at 1:1000.

ILT6/CD85e/LILRA3 Antibody - NBP1-98549 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ILT6/CD85e/LILRA3 Antibody [NBP1-98549] - Antibody Dilution: 1.0ug/ml Sample Tissue: Human Kidney.

ILT6/CD85e/LILRA3 Antibody - H00011026-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ILT6/CD85e/LILRA3 Antibody - H00011026-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ILT6/CD85e/LILRA3 Antibody [H00011026-B01P] - Analysis of LILRA3 expression in transfected 293T cell line by LILRA3 polyclonal antibody. Lane 1: LILRA3 transfected lysate(48.29 KDa). Lane 2: Non-transfected lysate.

ILT6/CD85e/LILRA3 Antibody [Alexa Fluor (R) 488] - IC2574G from Novus Biologicals

Host Goat
Clonality Polyclonal

Anti-LILRA3 antibody produced in rabbit - SAB1410149 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-LILRA3: <B>Cat. No. SAB1410149</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~47.5 kDa using LILRA3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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