LILRA3

Gene Symbol LILRA3
Entrez Gene 11026
Alt Symbol CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4
Species Human
Gene Type protein-coding
Description leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Other Description CD85 antigen-like family member E|immunoglobulin-like transcript 6|leukocyte immunoglobulin-like receptor 4|leukocyte immunoglobulin-like receptor A3|leukocyte immunoglobulin-like receptor subfamily A member 3|monocyte inhibitory receptor HM43/HM31
Swissprots Q8N6C8 Q8N151 Q8NHJ3 Q8NHJ1 Q8NHJ2 Q8N154 J3KPM2 O15469 O75016 Q8NHJ4 O15470
Accessions AAK58867 AAM18035 AAM18036 AAM18037 AAM18038 AAM18039 AAM18040 AAM18041 AAM18042 CCF76528 CCF76529 EAW72225 Q8N6C8 AF014923 AAC51885 AF014924 AAC51886 AF025527 AAB87661 AI655471 BC028208 AAH28208 BX280714 DQ891075 ABM82001 DQ894258 ABM85184 U91926 AAB68666 U91927 AAB68667 XM_005277092 XP_005277149 XM_011547082 XP_011545384 XM_011547083 XP_011545385 XM_011547084 XP_011545386 XM_011547085 XP_011545387 XM_011547086 XP_011545388 XM_011547087 XP_011545389 XM_011547088 XP_011545390 XM_011547503 XP_011545805 XM_011547504 XP_011545806 XM_011547505 XP_011545807 XM_011547506 XP_011545808 XM_011547507 XP_011545809 XM_011548673 XP_011546975 XM_011548674 XP_011546976 XM_011548675 XP_011546977 XM_011548676 XP_011546978 XM_011548677 XP_011546979 NM_001172654 NP_001166125 NM_006865 NP_006856
Function Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes. {ECO:0000269|PubMed:21559424, ECO:0000269|PubMed:24085305}.
Subcellular Location Secreted {ECO:0000305}.
Tissue Specificity Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung. {ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}.
Top Pathways Osteoclast differentiation

Human LILRA3 full length protein - ab161250 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161250 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human LILRA3 full length protein - ab192288 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Human LILRA3 protein fragment - ab161251 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161251 on a 12.5% SDS-PAGE stained with Coomassie Blue.

LILRA3 / CD85e Antibody Blocking Peptide - LS-E23785 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LILRA3 / CD85e Antibody Blocking Peptide - LS-E23786 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human ILT6/CD85e/LILRA3 Protein - H00011026-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human ILT6/CD85e/LILRA3 Protein - H00011026-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human
SDS-Page: ILT6/CD85e/LILRA3 Recombinant Protein [H00011026-P01]

Human CD 85E protein - orb139278 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Human Cells
Species Human
SDS-PAGE analysis of Human LILRA3 protein (His Tag)

Human ILT6 protein - orb180292 from Biorbyt

Category Protein
Prices $289.00, $621.00, $2,321.00, $3,281.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Species Human

Human LILRA3 Protein - abx067777 from Abbexa

Category Protein
Source E.coli
Species Human

CD85e / LILRA3 - H00011026-P01-02 from Acris Antibodies

Category Protein
Prices $300.00
Sizes 2 µg
Source in vitro transl.
Species Human

CD85e / LILRA3 - H00011026-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CD85e / LILRA3 - H00011026-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

LILRA3 Recombinant Protein - 96-516 from ProSci

Category Protein
Prices $450.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh LILRA3 / ILT6 Fc Chimera was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

LILRA3 fusion protein - ag5601 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

Recombinant Human LILRA3, Fc tagged - LILRA3-8597H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human LILRA3, His tagged - LILRA3-311H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) - RPB387Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Human ILT6 / LILRA3 Protein (Fc Tag) - 13549-H02H-20 from Sino Biological

Category Protein
Prices $158.00, $298.00
Sizes 20 µg, 50 µg
Source Human Cells
Species Human

Human ILT6 / LILRA3 Protein (His Tag) - 13549-H08H-100 from Sino Biological

Category Protein
Prices $138.00, $348.00
Sizes 20 µg, 100 µg
Source Human Cells
Species Human

Human LILRA3 / CD85e Protein, Fc Tag - LI3-H5256 from ACROBiosystems

Category Protein
Prices $315.00, $1,800.00
Sizes 100 µg, 1 mg (500ug x 2)
Source Human LILRA3, Fc Tag (LI3-H5256) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 439 (Accession # AAH28208).
Species Human

Recombinant Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) - RPB387Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Leukocyte immunoglobulin-like receptor subfamily A member 3(LI - CSB-YP836677HU CSB-EP836677HU CSB-BP836677HU CSB-MP836677HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CD85e / LILRA3 - TP307003 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CD85e / LILRA3

CD85e / LILRA3 (transcript variant 1) - TP721110 from Acris Antibodies

Category Protein
Prices $139.00
Sizes 10 µg
Source HEK293 cells
Species Human
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