LILRA3

Gene Symbol	LILRA3
Entrez Gene	11026
Alt Symbol	CD85E, HM31, HM43, ILT-6, ILT6, LIR-4, LIR4
Species	Human
Gene Type	protein-coding
Description	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Other Description	CD85 antigen-like family member E|immunoglobulin-like transcript 6|leukocyte immunoglobulin-like receptor 4|leukocyte immunoglobulin-like receptor A3|leukocyte immunoglobulin-like receptor subfamily A member 3|monocyte inhibitory receptor HM43/HM31
Swissprots	Q8N6C8 Q8N151 Q8NHJ3 Q8NHJ1 Q8NHJ2 Q8N154 J3KPM2 O15469 O75016 Q8NHJ4 O15470
Accessions	AAK58867 AAM18035 AAM18036 AAM18037 AAM18038 AAM18039 AAM18040 AAM18041 AAM18042 CCF76528 CCF76529 EAW72225 Q8N6C8 AF014923 AAC51885 AF014924 AAC51886 AF025527 AAB87661 AI655471 BC028208 AAH28208 BX280714 DQ891075 ABM82001 DQ894258 ABM85184 U91926 AAB68666 U91927 AAB68667 XM_005277092 XP_005277149 XM_011547082 XP_011545384 XM_011547083 XP_011545385 XM_011547084 XP_011545386 XM_011547085 XP_011545387 XM_011547086 XP_011545388 XM_011547087 XP_011545389 XM_011547088 XP_011545390 XM_011547503 XP_011545805 XM_011547504 XP_011545806 XM_011547505 XP_011545807 XM_011547506 XP_011545808 XM_011547507 XP_011545809 XM_011548673 XP_011546975 XM_011548674 XP_011546976 XM_011548675 XP_011546977 XM_011548676 XP_011546978 XM_011548677 XP_011546979 NM_001172654 NP_001166125 NM_006865 NP_006856
Function	Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes. {ECO:0000269|PubMed:21559424, ECO:0000269|PubMed:24085305}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung. {ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LILRA3-Over-expression-Lysate - LY14690a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

LILRA3 / CD85e Lysate (Non-Denatured) - L131T6 from Acris Antibodies Category Cell Lysate Prices $290.00 Sizes 100 µg

LILRA3 293T Cell Transient Overexpression Lysate(Denatured) - H00011026-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

LILRA3 overexpression lysate - LY416372 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LILRA3 overexpression lysate - LY432960 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LILRA3 293 Cell Lysate - 407655 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ILT6/CD85e/LILRA3 Overexpression Lysate (Native) - NBL1-12525 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

LILRA3 Over-expression Lysate Product - GWB-3B8697 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human ILT6 / LILRA3 HEK293 Cell Lysate (WB positive control) - 13549-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human ILT6 / LILRA3 HEK293 Cell Lysate (WB positive control) - 13549-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human LILRA3 Human Cells Transfected Lysate (positive control) (denatured) - orb174684 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

ILT6/CD85e/LILRA3 Overexpression Lysate (Denatured) - H00011026-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ILT6/CD85e/LILRA3 Overexpression Lysate (Denatured) - H00011026-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Human LILRA3 Human Cells Transfected Lysate (positive control) (denatured) - orb174325 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human LILRA3 Knockdown Stable Cell Line - CSC-DC008702 from Creative biogene Category Cell Line Species Human

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