IFIT5

Gene Symbol	IFIT5
Entrez Gene	24138
Alt Symbol	ISG58, P58, RI58
Species	Human
Gene Type	protein-coding
Description	interferon-induced protein with tetratricopeptide repeats 5
Other Description	IFIT-5|interferon-induced 58 kDa protein|retinoic acid- and interferon-inducible 58 kDa protein|retinoic acid- and interferon-inducible protein (58kD)
Swissprots	Q6IAX3 Q5T7I9 B4DDV1 B2R5X9 Q13325
Accessions	EAW50135 Q13325 AK293346 BAG56862 AK312358 BAG35276 BC025786 AAH25786 CR457031 CAG33312 DC392439 U34605 AAA84934 NM_012420 NP_036552
Function	Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs. {ECO:0000269|PubMed:23317505, ECO:0000269|PubMed:23334420}.
Subcellular Location	Cell projection, ruffle membrane {ECO:0000269|PubMed:23317505}. Note=Colocalized with DDX58/RIG-I at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IFIT5 full length protein - ab132670 from Abcam Category Protein Source Wheat germ Species Human

Human IFIT5 protein fragment - ab127296 from Abcam Category Protein Source E. coli Species Human

IFIT5 Antibody Blocking Peptide - LS-E19798 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IFIT5 Protein - H00024138-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IFIT5 Blocking Peptide - 33R-4192 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

IFIT5 Blocking Peptide - 33R-4886 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

IFIT5 - H00024138-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

IFIT5 - H00024138-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

IFIT5 fusion protein - ag4202 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IFIT-5 (L319) Peptide - BS9267P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Interferon-induced protein with tetratricopeptide repeats 5(IF - CSB-YP011023HU CSB-EP011023HU CSB-BP011023HU CSB-MP011023HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

IFIT5 - TP306499 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

IFIT5 Recombinant Protein Antigen - NBP1-87132PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

IFIT5 Blocking Peptide - abx162122 from Abbexa Category Peptide Species Human, Mouse

IFIT5 Peptide, Human - M34GP07429H from Creative Peptides Category Peptide Source Synthetic. Species Human

IFIT5 Blocking Peptide - CBP4911 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

IFIT5 peptide - orb316055 from Biorbyt Category Peptide Prices $247.00, $510.00 Sizes 1 mg, 5 mg

Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), Recombinant Protein - MBS1359948 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,535.00, $2,535.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

IFIT5 Recombinant Protein Antigen - NBP2-56869PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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