IFIT5

Gene Symbol IFIT5
Entrez Gene 24138
Alt Symbol ISG58, P58, RI58
Species Human
Gene Type protein-coding
Description interferon-induced protein with tetratricopeptide repeats 5
Other Description IFIT-5|interferon-induced 58 kDa protein|retinoic acid- and interferon-inducible 58 kDa protein|retinoic acid- and interferon-inducible protein (58kD)
Swissprots Q6IAX3 Q5T7I9 B4DDV1 B2R5X9 Q13325
Accessions EAW50135 Q13325 AK293346 BAG56862 AK312358 BAG35276 BC025786 AAH25786 CR457031 CAG33312 DC392439 U34605 AAA84934 NM_012420 NP_036552
Function Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs. {ECO:0000269|PubMed:23317505, ECO:0000269|PubMed:23334420}.
Subcellular Location Cell projection, ruffle membrane {ECO:0000269|PubMed:23317505}. Note=Colocalized with DDX58/RIG-I at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface.

IFIT5 (N-14) - sc-104940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IFIT5 (N-14): sc-104940. Western blot analysis of IFIT5 expression in T24 whole cell lysate.

IFIT5 (E-15) - sc-104938 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IFIT5 antibody - ab113485 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab113485 at 1/100 dilution staining IFIT5 in Formalin-fixed, Paraffin-embedded Human fetal brain tissue by Immunohistochemistry.

Anti-IFIT5 antibody - ab81694 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IFIT5 antibody (ab81694) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-IFIT5 antibody - ab136857 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IFIT5 antibody (ab136857) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-IFIT5 antibody - ab167272 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-IFIT5 antibody (ab167272) at 1 µg/mlLane 1 : IFIT5 transfected 293T cell lysateLane 2 : Non-transfected lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-IFIT5 Antibody (Leu319) - LS-C193267 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IFIT5 Antibody (aa270-319) - LS-C292085 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IFIT5 Antibody - LS-C308388 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-IFIT5 Antibody (aa182-231) - LS-C81958 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-IFIT5 Antibody (aa110-159) - LS-C81957 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-IFIT5 Antibody (aa79-294) - LS-C178516 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IFIT5 Antibody - NBP1-87132 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IFIT5 Antibody - NBP1-58887 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

IFIT5 Antibody - NBP1-58886 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IFIT5 Antibody [NBP1-58886] - Titration: 0.2-1 ug/ml, Positive Control: Jurkat cell lysate.

IFIT5 Antibody - H00024138-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: IFIT5 Antibody [H00024138-B01P] - Analysis of IFIT5 expression in transfected 293T cell line by IFIT5 polyclonal antibody. Lane 1: IFIT5 transfected lysate(53.02 KDa). Lane 2: Non-transfected lysate.

Rabbit Anti-IFIT5 Polyclonal Antibody - bs-15516R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IFIT5 antibody produced in mouse - SAB1409040 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IFIT5: <B>Cat. No. SAB1409040</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~53 kDa using IFIT5 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-IFIT5 (386-400) antibody produced in rabbit - SAB1101560 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-IFIT5 (386-400) (RB): <B>Cat. No. SAB1101560</B>: Immunofluorescence of HUVEC cells using Anti-IFIT5 (386-400) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-IFIT5 (ab2) antibody produced in rabbit - SAB2101130 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IFIT5 (ab2): <B>Cat. No.SAB2101130</B>: IFIT5 in Jurkat cell lysate with IFIT5 antibody at 1.0 μg/mL.

Anti-IFIT5 (ab1) antibody produced in rabbit - SAB2101129 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IFIT5 (ab1): <B>Cat. No.SAB2101129</B>: IFIT5 in MCF7 cell lysate with IFIT5 antibody at 1.0 μg/mL.

Anti-IFIT5 antibody produced in rabbit - HPA037957 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IFIT5: <B>Cat. No. HPA037957</B>: Immunohistochemical staining of human lateral ventricle shows strong cytoplasmic positivity in astrocytes.

IFIT5 antibody - N-terminal region (ARP54897_P050) - ARP54897_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IFIT5 antibody - middle region (ARP54898_P050) - ARP54898_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IFIT5 antibody, Internal - GTX45362 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-IFIT5 antibody, Internal used in Western blot. GTX45362
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