IFIT5

Gene Symbol IFIT5
Entrez Gene 24138
Alt Symbol ISG58, P58, RI58
Species Human
Gene Type protein-coding
Description interferon-induced protein with tetratricopeptide repeats 5
Other Description IFIT-5|interferon-induced 58 kDa protein|retinoic acid- and interferon-inducible 58 kDa protein|retinoic acid- and interferon-inducible protein (58kD)
Swissprots Q6IAX3 Q5T7I9 B4DDV1 B2R5X9 Q13325
Accessions EAW50135 Q13325 AK293346 BAG56862 AK312358 BAG35276 BC025786 AAH25786 CR457031 CAG33312 DC392439 U34605 AAA84934 NM_012420 NP_036552
Function Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs. {ECO:0000269|PubMed:23317505, ECO:0000269|PubMed:23334420}.
Subcellular Location Cell projection, ruffle membrane {ECO:0000269|PubMed:23317505}. Note=Colocalized with DDX58/RIG-I at cell surface ruffles. Localizes to actin-rich protrusions from the apical cell surface.

IFIT5 CRISPR/Cas9 KO Plasmid (h) - sc-406044 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 HDR Plasmid (h) - sc-406044-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 Double Nickase Plasmid (h) - sc-406044-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 Double Nickase Plasmid (h2) - sc-406044-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 CRISPR Activation Plasmid (h) - sc-406044-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 CRISPR Activation Plasmid (h2) - sc-406044-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 Lentiviral Activation Particles (h) - sc-406044-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 Lentiviral Activation Particles (h2) - sc-406044-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IFIT5 siRNA (h) - sc-90427 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFIT5 shRNA Plasmid (h) - sc-90427-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IFIT5 shRNA (h) Lentiviral Particles - sc-90427-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU044531 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10469 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10469 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11330 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11330

IFIT5 siRNA (Human) - CRH8467 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IFIT5 - MBS8228848 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IFIT5 (NM_012420.2) - SHH316945 from Creative biogene

Category siRNA
Species Reactivities Human

IFIT5 shRNA Plasmid (Human) - CHH8467 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IFIT5 miRNA 3'UTR clone - MiUTR4H-TG04409 from Creative biogene

Species Reactivities Human
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