STEAP2

Gene Symbol STEAP2
Entrez Gene 261729
Alt Symbol IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
Species Human
Gene Type protein-coding
Description STEAP family member 2, metalloreductase
Other Description SixTransMembrane Protein of Prostate 1|metalloreductase STEAP2|prostate cancer associated protein 1|prostate cancer-associated protein 1|protein up-regulated in metastatic prostate cancer|protein upregulated in metastatic prostate cancer|six transmembrane epithelial antigen of prostate 2|six transmembrane epithelial antigen of the prostate 2|six-transmembrane epithelial antigen of prostate 2
Swissprots Q6YPB1 Q8IUE7 Q6UXN6 A4D1F1 G5E9C6 Q8NFT2
Accessions EAL24165 EAW76889 EAW76890 EAW76891 EAW76892 EAW76893 EAW76894 Q8NFT2 AF455138 AAN04080 AF526382 AAQ08976 AK026813 AK092666 BAG52586 AK094568 AK315043 BAG37524 AY008443 AAG32147 AY008444 AAG32148 AY358267 AAQ88634 BC146341 AAI46342 BC148824 AAI48825 DQ656061 DQ656062 DR005432 XM_006715921 XP_006715984 NM_001040665 NP_001035755 NM_001040666 NP_001035756 NM_001244944 NP_001231873 NM_001244945 NP_001231874 NM_001244946 NP_001231875 NM_152999 NP_694544
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity). {ECO:0000250}.
Subcellular Location Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:12429817}; Multi-pass membrane protein {ECO:0000269|PubMed:12429817}.
Tissue Specificity Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary. {ECO:0000269|PubMed:12095985, ECO:0000269|PubMed:12429817, ECO:0000269|PubMed:16609065}.
Top Pathways Mineral absorption

STEAP2 (H-64) - sc-368248 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

STEAP2 (N-16) - sc-82365 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

STEAP2 (S-19) - sc-82367 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-STEAP2 antibody - ab174978 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STEAP2 antibody (ab174978) at 1/100 dilutionLane 1 : Mouse spleen tissue lysateLane 2 : Mouse liver tissue lysateLane 3 : 293 cell lysateLysates/proteins at 15 µg per lane.

Anti-STEAP2 antibody - ab196661 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent  analysis of A549 cells labeling STEAP2 with ab196661 at 1/100 dilution

Anti-STEAP2 antibody - ab133392 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of STEAP2 in formalin fixed and paraffin ebedded Human uterus tissue labelled with ab133392 at 10 µg/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-STEAP2 antibody - C-terminal - ab188811 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of formalin-fixed, paraffin-embedded Human uterus tissue labelling STEAP2 with ab188811 at 20 µg/ml.

Anti-STEAP2 Antibody (C-Terminus) IHC-plus™ - LS-B1405 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1405 concentration 10 ug/ml.

Anti-STEAP2 Antibody (aa233-262) - LS-C161555 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
STEA2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-STEAP2 Antibody (C-Terminus) IHC-plus™ - LS-A9242 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP2 antibody LS-A9242 IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-STEAP2 Antibody (Internal) IHC-plus™ - LS-A9239 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP2 antibody LS-A9239 IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-STEAP2 Antibody (C-Terminus) IHC-plus™ - LS-A9241 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP2 antibody LS-A9241 IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-STEAP2 Antibody (aa233-262, AP) - LS-C241350 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa233-262, APC) - LS-C241351 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa233-262, Biotin) - LS-C241352 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa233-262, FITC) - LS-C241353 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa233-262, PE) - LS-C241357 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa431-480) - LS-C119155 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using STEA2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-STEAP2 Antibody (aa233-262, Azide-free, HRP) - LS-C248270 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa233-262) - LS-C325442 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-STEAP2 Antibody (aa71-120) - LS-C201323 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HepG2. STEAP2 antibody dilution 1.0 ug/ml.

Anti-STEAP2 Antibody (aa455-467) IHC-plus™ - LS-B5085 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5085 concentration 10 ug/ml.

STEAP2 Antibody - NB100-80829 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: STEAP2 Antibody [NB100-80829] -  Human prostate tissue lysate with STEAP2 antibody at 1 ug/ml.

STEAP2 Antibody - NBP1-76823 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: STEAP2 Antibody [NBP1-76823] - Analysis in human prostate tissue lysate with antibody at 1 ug/mL.

STEAP2 Antibody - NBP1-83100 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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