Gene Symbol | F13A1 |
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Entrez Gene | 2162 |
Alt Symbol | F13A |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor XIII, A1 polypeptide |
Other Description | FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII A chain|coagulation factor XIII, A polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma |
Swissprots | Q8N6X2 Q59HA7 Q96P24 P00488 Q9BX29 |
Accessions | AAA52415 AAF65991 AAL12161 AAR97735 ABJ51931 CAA00294 EAW55185 EAW55186 P00488 AB208852 BAD92089 AK130666 AK304335 BAG65180 AK312735 BAG35606 BC027963 AAH27963 BP251770 DQ893561 ABM84487 DQ894109 ABM85035 EU176539 ABW03340 M14354 AAA52488 M14539 AAA52489 XM_006715010 XP_006715073 XM_011514342 XP_011512644 NM_000129 NP_000120 |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Subcellular Location | Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. |
Top Pathways | Complement and coagulation cascades |
Factor XIII A (B-8) - sc-376312 from Santa Cruz Biotechnology
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Factor XIII A (C-20) - sc-18013 from Santa Cruz Biotechnology
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Factor XIII A (A-4) - sc-271122 from Santa Cruz Biotechnology
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Factor XIII A (H-47) - sc-292288 from Santa Cruz Biotechnology
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Anti-Factor XIII/XIIIa antibody - ab45000 from Abcam
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Anti-Factor XIII/XIIIa antibody [9E2] - ab131646 from Abcam
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Anti-Factor XIIIa antibody - ab97636 from Abcam
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Anti-Factor XIIIa antibody - ab77274 from Abcam
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Anti-Factor XIIIa antibody - ab4057 from Abcam
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Anti-Factor XIIIa antibody - ab104558 from Abcam
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Anti-Factor XIIIa antibody - ab104559 from Abcam
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Anti-Factor XIIIa antibody - ab88905 from Abcam
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Anti-Factor XIIIa antibody [AC-1A1] - ab1834 from Abcam
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Anti-Factor XIIIa antibody [AC-1A1], prediluted - ab15207 from Abcam
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Anti-Factor XIIIa antibody [EP3371] - ab79759 from Abcam
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Anti-Factor XIIIa antibody [EP3372] - ab76105 from Abcam
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Anti-Factor XIIIa antibody [EPR10360] - ab179444 from Abcam
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Anti-Factor XIIIa antibody, prediluted - ab75304 from Abcam
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Anti-Factor XIIIa antibody - Cleaved-Gly39 - ab199601 from Abcam
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Anti-F13A1 / Factor XIIIa Antibody (clone 6F5) - LS-C175252 from LifeSpan Bioscience
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Anti-F13A1 / Factor XIIIa Antibody (clone 3F1) - LS-C175253 from LifeSpan Bioscience
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Anti-F13A1 / Factor XIIIa Antibody - LS-C23422 from LifeSpan Bioscience
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Anti-F13A1 / Factor XIIIa Antibody (HRP) - LS-C23423 from LifeSpan Bioscience
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Anti-F13A1 / Factor XIIIa Antibody (HRP) - LS-C23426 from LifeSpan Bioscience
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Anti-F13A1 / Factor XIIIa Antibody - LS-C23427 from LifeSpan Bioscience
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