Gene Symbol | F13A1 |
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Entrez Gene | 2162 |
Alt Symbol | F13A |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor XIII, A1 polypeptide |
Other Description | FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII A chain|coagulation factor XIII, A polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma |
Swissprots | Q8N6X2 Q59HA7 Q96P24 P00488 Q9BX29 |
Accessions | AAA52415 AAF65991 AAL12161 AAR97735 ABJ51931 CAA00294 EAW55185 EAW55186 P00488 AB208852 BAD92089 AK130666 AK304335 BAG65180 AK312735 BAG35606 BC027963 AAH27963 BP251770 DQ893561 ABM84487 DQ894109 ABM85035 EU176539 ABW03340 M14354 AAA52488 M14539 AAA52489 XM_006715010 XP_006715073 XM_011514342 XP_011512644 NM_000129 NP_000120 |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Subcellular Location | Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. |
Top Pathways | Complement and coagulation cascades |
Human Factor XIII full length protein - ab158413 from Abcam
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Human Factor XIIIa full length protein - ab167813 from Abcam
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Human Factor XIIIa full length protein - ab62412 from Abcam
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F13A1 / Factor XIIIa Antibody Blocking Peptide - LS-E26471 from LifeSpan Bioscience
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F13A1 / Factor XIIIa Antibody Blocking Peptide - LS-E26472 from LifeSpan Bioscience
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Recombinant Human Factor XIIIa Protein - H00002162-P01 from Novus Biologicals
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Factor-XIIIa-Antibody-C-term-Blocking-Peptide - BP6735b from Abgent, a WuXi AppTec company
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Factor XIIIa Peptide - AC21-1309-P from Abcore
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Coagulation factor XIIIa (F13A1) - H00002162-P01-10 from Acris Antibodies
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Coagulation factor XIIIa (F13A1) - H00002162-P01-25 from Acris Antibodies
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Factor XIII alpha Peptide - 45-564P from ProSci
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F13A1 fusion protein - Ag11105 from Proteintech Group
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F13A1 fusion protein - ag11059 from Proteintech Group
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Recombinant Human F13A1, His-tagged - F13A1-12618H from Creative Biomart
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Native Human F13A1 - F13A1-28806TH from Creative Biomart
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Native Human Coagulation Factor XIII, A1 Polypeptide - F13A1-5399H from Creative Biomart
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Native Human Coagulation Factor XIII, A1 Polypeptide - F13A1-1881H from Creative Biomart
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Human coagulation Factor XIII - HFXIII from Molecular Innovations
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Human coagulation Factor XIIIa - HFXIIIA from Molecular Innovations
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Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Hu01 from Uscn Life Science Inc.
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Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Mu01 from Uscn Life Science Inc.
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Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) - RPB094Ra01 from Uscn Life Science Inc.
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Coagulation Factor XIIIA (72-97) - 02180301 from MP Biomedicals
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Factor XIII A Blocking Peptide - CBP1410 from Cohesion Biosciences
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Factor 13 A (G39) Peptide - BS7027P from Bioworld Technology
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