F13A1

Gene Symbol F13A1
Entrez Gene 2162
Alt Symbol F13A
Species Human
Gene Type protein-coding
Description coagulation factor XIII, A1 polypeptide
Other Description FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII A chain|coagulation factor XIII, A polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma
Swissprots Q8N6X2 Q59HA7 Q96P24 P00488 Q9BX29
Accessions AAA52415 AAF65991 AAL12161 AAR97735 ABJ51931 CAA00294 EAW55185 EAW55186 P00488 AB208852 BAD92089 AK130666 AK304335 BAG65180 AK312735 BAG35606 BC027963 AAH27963 BP251770 DQ893561 ABM84487 DQ894109 ABM85035 EU176539 ABW03340 M14354 AAA52488 M14539 AAA52489 XM_006715010 XP_006715073 XM_011514342 XP_011512644 NM_000129 NP_000120
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Subcellular Location Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Top Pathways Complement and coagulation cascades

Factor XIII A CRISPR/Cas9 KO Plasmid (h) - sc-402690 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A HDR Plasmid (h) - sc-402690-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A Double Nickase Plasmid (h) - sc-402690-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A Double Nickase Plasmid (h2) - sc-402690-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A CRISPR Activation Plasmid (h) - sc-402690-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A CRISPR Activation Plasmid (h2) - sc-402690-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A Lentiviral Activation Particles (h) - sc-402690-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A Lentiviral Activation Particles (h2) - sc-402690-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Factor XIII A siRNA (h) - sc-72083 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XIII A shRNA Plasmid (h) - sc-72083-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XIII A shRNA (h) Lentiviral Particles - sc-72083-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Factor XIIIa RNAi - H00002162-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU028951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1631 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1631 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09763 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09763

F13A1 siRNA (Human) - CRH1504 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F13A1 - MBS8229624 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human F13A1 (NM_000129.3) - SHH288405 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human F13A1(NM_000129.3) - SHH043355 from Creative biogene

Category siRNA
Species Reactivities Human

Human F13A1 siRNA - orb262006 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F13A1 shRNA Plasmid (Human) - CHH1504 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

F13A1 miRNA 3'UTR clone - MiUTR1H-03361 from Creative biogene

Species Reactivities Human
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