Gene Symbol | F13A1 |
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Entrez Gene | 2162 |
Alt Symbol | F13A |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor XIII, A1 polypeptide |
Other Description | FSF, A subunit|TGase|bA525O21.1 (coagulation factor XIII, A1 polypeptide)|coagulation factor XIII A chain|coagulation factor XIII, A polypeptide|coagulation factor XIIIa|factor XIIIa|fibrin stabilizing factor, A subunit|fibrinoligase|protein-glutamine gamma-glutamyltransferase A chain|transglutaminase A chain|transglutaminase. plasma |
Swissprots | Q8N6X2 Q59HA7 Q96P24 P00488 Q9BX29 |
Accessions | AAA52415 AAF65991 AAL12161 AAR97735 ABJ51931 CAA00294 EAW55185 EAW55186 P00488 AB208852 BAD92089 AK130666 AK304335 BAG65180 AK312735 BAG35606 BC027963 AAH27963 BP251770 DQ893561 ABM84487 DQ894109 ABM85035 EU176539 ABW03340 M14354 AAA52488 M14539 AAA52489 XM_006715010 XP_006715073 XM_011514342 XP_011512644 NM_000129 NP_000120 |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Subcellular Location | Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma. |
Top Pathways | Complement and coagulation cascades |
F13A1 293T Cell Transient Overexpression Lysate(Denatured) - H00002162-T01 from Acris Antibodies
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F13A1 overexpression lysate - LY400044 from Acris Antibodies
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F13A1 293 Cell Lysate - 400139 from ABBIOTEC
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Factor XIIIa Overexpression Lysate (Denatured) - H00002162-T01 from Novus Biologicals
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Factor XIIIa Overexpression Lysate (Native) - NBL1-10406 from Novus Biologicals
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Factor XIII A (h): 293T Lysate - sc-114126 from Santa Cruz Biotechnology
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F13A1 Over-expression Lysate Product - GWB-C9DC73 from Genway Biotech
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Human Factor XIII (Factor 13) Deficient Plasma (EDTA) - D101305 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (EDTA) - D101306 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (EDTA) - D101304 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Heparin) - D101307 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Heparin) - D101308 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Heparin) - D101309 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Sodium Citrate) - D101301 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Sodium Citrate) - D101302 from AssayPro
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Human Factor XIII (Factor 13) Deficient Plasma (Sodium Citrate) - D101303 from AssayPro
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Human Factor XIII (Factor 13) Deficient Serum - D101310 from AssayPro
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Human Factor XIII (Factor 13) Deficient Serum - D101311 from AssayPro
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Human Factor XIII (Factor 13) Deficient Serum - D101312 from AssayPro
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Panoply™ Human F13A1 Knockdown Stable Cell Line - CSC-DC005168 from Creative biogene
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