GPR35

Gene Symbol GPR35
Entrez Gene 2859
Alt Symbol -
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 35
Other Description G-protein coupled receptor 35|KYNA receptor|kynurenic acid receptor
Swissprots Q4VBN5 Q86UH4 Q9HC97 O43495 J3KR30 Q6FHI8 Q17R58 Q4ZFV2
Accessions AAC52028 AAP32299 AAX88945 EAW71209 EAW71210 Q9HC97 AF089087 AAG17965 AK131540 BAD18676 AK172786 AK290256 BAF82945 AK314002 BAG36714 AW000832 BC095500 AAH95500 BC117453 AAI17454 BC117455 AAI17456 BM857130 CR541765 CAG46564 DB011311 NM_001195381 NP_001182310 NM_001195382 NP_001182311 NM_005301 NP_005292
Function Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. {ECO:0000269|PubMed:16754668}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16754668}; Multi-pass membrane protein {ECO:0000269|PubMed:16754668}. Note=Internalized to the cytoplasm after exposure to kynurenic acid.
Tissue Specificity Predominantly expressed in immune and gastrointestinal tissues. {ECO:0000269|PubMed:16754668}.
Top Pathways Neuroactive ligand-receptor interaction

GPR35 (H-79) - sc-292298 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

GPR35 (S-13) - sc-79510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GPR35 (S-13): sc-79510. Western blot analysis of GPR35 expression in MCF7 (A), HEK293 (B), Jurkat (C) and K-562 (D) whole cell lysates.

GPR35 (T-14) - sc-79511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-GPCR GPR35 antibody - ab150635 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human pancreas tissue labeling GPCR GPR35 with ab150635 at 23 &microg/ml after heat induced antigen retrieval.

Anti-GPCR GPR35 antibody - ab76217 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GPCR GPR35 antibody (ab76217) at 1/500 dilutionLane 1 : extracts from LOVO cellsLane 2 : extracts from LOVO cells with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-GPCR GPR35 antibody - ab133961 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GPCR GPR35 antibody (ab133961) at 1 µg/ml + HT1080 cell lysate at 10 µg

Anti-GPCR GPR35 antibody - Cytoplasmic domain - ab188949 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded human pancreas tissue labeling GPCR GPR35 using ab188949 at 9 µg/ml.

Anti-GPR35 Antibody (aa8-21) - LS-C148935 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-GPR35 Antibody (Extracellular Domain) IHC-plus™ - LS-A125 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR35 antibody LS-A125 IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR35 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A2 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR35 antibody LS-A2 IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR35 Antibody (C-Terminus) - LS-C151780 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GPR35 antibody Western Blot of MCF7.

Anti-GPR35 Antibody (aa275-325) - LS-C148427 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of ug Protein-Coupled Receptor GPR35 in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide 3) RAW using LS-C148427 at 0.5 ug/ml and 1.0 ug/ml, respectively.

Anti-GPR35 Antibody IHC-plus™ - LS-B6937 from LifeSpan Bioscience

Prices $395.00
Sizes 1 ea
Host Rabbit
Clonality Polyclonal
Anti-GPR35 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6937 concentration 5 ug/ml.

Anti-GPR35 Antibody (aa199-248) - LS-C151781 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GPR35 antibody Western Blot of HT1080.

Anti-GPR35 Antibody - LS-C332670 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of A549 cell line, using GPR35 antibody.

Anti-GPR35 Antibody (aa51-100) - LS-C120718 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using GPR35 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-GPR35 Antibody (C-Terminus) IHC-plus™ - LS-A3 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR35 antibody LS-A3 IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR35 Antibody - NBP2-24640 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

GPR35 Antibody - NLS3 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: GPR35 Antibody [NLS3] - Analysis of anti-GPR35 antibody with transfected HEK293 human embryonic kidney cells at 12 ug/ml.

GPR35 Antibody - NBP1-71082 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GPR35 Antibody [NBP1-71082] - Analysis of extracts from LOVO cells, using GPR35 Antibody. The lane on the right is treated with the synthesized peptide.

GPR35 Antibody - NLS3975 from Novus Biologicals

Prices $369.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR35 Antibody [NLS3975] - Analysis of transfected cells expressing GPR35 using NLS3975 at 28 ug/ ml.

GPR35 Antibody - NLS2 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR35 Antibody [NLS2] - Analysis of anti-GPR35 antibody with human pancreas at 5 ug/ml.

GPR35 Antibody - NLS5100 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

GPR35 Antibody - NLS125 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: GPR35 Antibody [NLS125] - Analysis of anti-GPR35 antibody with human pancreas at 9 ug/ml.

GPR35 Polyclonal Antibody - bs-13533R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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