GPR35

Gene Symbol GPR35
Entrez Gene 2859
Alt Symbol -
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 35
Other Description G-protein coupled receptor 35|KYNA receptor|kynurenic acid receptor
Swissprots Q4VBN5 Q86UH4 Q9HC97 O43495 J3KR30 Q6FHI8 Q17R58 Q4ZFV2
Accessions AAC52028 AAP32299 AAX88945 EAW71209 EAW71210 Q9HC97 AF089087 AAG17965 AK131540 BAD18676 AK172786 AK290256 BAF82945 AK314002 BAG36714 AW000832 BC095500 AAH95500 BC117453 AAI17454 BC117455 AAI17456 BM857130 CR541765 CAG46564 DB011311 NM_001195381 NP_001182310 NM_001195382 NP_001182311 NM_005301 NP_005292
Function Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. {ECO:0000269|PubMed:16754668}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16754668}; Multi-pass membrane protein {ECO:0000269|PubMed:16754668}. Note=Internalized to the cytoplasm after exposure to kynurenic acid.
Tissue Specificity Predominantly expressed in immune and gastrointestinal tissues. {ECO:0000269|PubMed:16754668}.
Top Pathways Neuroactive ligand-receptor interaction

GPR35 CRISPR/Cas9 KO Plasmid (h) - sc-416792 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 HDR Plasmid (h) - sc-416792-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 Double Nickase Plasmid (h) - sc-416792-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 Double Nickase Plasmid (h2) - sc-416792-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 CRISPR Activation Plasmid (h) - sc-416792-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 CRISPR Activation Plasmid (h2) - sc-416792-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 Lentiviral Activation Particles (h) - sc-416792-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 Lentiviral Activation Particles (h2) - sc-416792-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GPR35 siRNA (h) - sc-75177 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR35 shRNA Plasmid (h) - sc-75177-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR35 shRNA (h) Lentiviral Particles - sc-75177-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GPR35 RNAi - H00002859-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9602 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9602 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02977 from Sigma-Aldrich

Category miRNA

GPR35 siRNA (Human) - CRH1919 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPR35 - MBS8202092 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPR35 (NM_005301.3) - SHH306806 from Creative biogene

Category siRNA
Species Reactivities Human

GPR35 shRNA Plasmid (Human) - CHH1919 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPR35 miRNA 3'UTR clone - MiUTR3H-05174 from Creative biogene

Species Reactivities Human
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