TPCN2

Gene Symbol TPCN2
Entrez Gene 219931
Alt Symbol SHEP10, TPC2
Species Human
Gene Type protein-coding
Description two pore segment channel 2
Other Description two pore calcium channel protein 2|two-pore calcium channel protein 2|voltage-dependent calcium channel protein TPC2
Swissprots Q9NT82 Q8NHX9
Accessions EAW74734 EAW74735 EAW74736 EAW74737 Q8NHX9 AB209253 BAD92490 AK023366 BAG51185 AK123089 AK298919 BAG61025 AL137479 CAB70760 AW177543 AY029200 AAK31802 BC063008 AAH63008 BP380645 CD636711 HG503921 HG503922 XM_005273824 XP_005273881 XM_005273826 XP_005273883 XM_005273827 XP_005273884 XM_005273828 XP_005273885 XM_005273830 XP_005273887 XM_005273831 XP_005273888 XM_005273832 XP_005273889 XM_006718453 XP_006718516 XM_006718454 XP_006718517 XM_006718456 XP_006718519 XM_011544802 XP_011543104 XM_011544803 XP_011543105 XM_011544804 XP_011543106 XM_011544805 XP_011543107 XM_011544806 XP_011543108 XM_011544807 XP_011543109 XM_011544808 XP_011543110 XR_247191 NM_139075 NP_620714
Function Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction. {ECO:0000269|PubMed:19387438, ECO:0000269|PubMed:19620632}.
Subcellular Location Lysosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Only the acidic lysosomal fraction is sensitive to NAADP. {ECO:0000250}.
Tissue Specificity Widely expressed. Expressed at high level in liver and kidney. {ECO:0000269|PubMed:19387438}.
Top Pathways Pancreatic secretion

TPCN2 (D-14) - sc-162344 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TPCN2 (G-15) - sc-162345 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TPCN2 (H-53) - sc-383009 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-Two pore calcium channel protein 2 antibody - ab119915 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Two pore calcium channel protein 2 antibody (ab119915) at 1/500 dilution + MCF7 cell lysate

Anti-Two pore calcium channel protein 2 antibody - ab111145 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111145, at 3.75 µg/ml, staining Two pore calcium channel protein 2 in formalin fixed, paraffin embedded Human colon tissue by Immunohistochemistry. Followed by biotinylated secondary antibody, alkaline phosphatase streptavidin and chromogen.

Anti-TPC2 / TPCN2 Antibody (aa700-752) - LS-C95186 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (aa240-252) - LS-C3241 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (aa727-740) - LS-C3240 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (Cytoplasmic Domain) - LS-C95187 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (Cytoplasmic Domain) - LS-C95188 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (N-Terminus) - LS-C178859 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TPC2 / TPCN2 Antibody (aa735-747) IHC-plus™ - LS-B4183 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TPCN2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4183 concentration 3.75 ug/ml.

Two pore calcium channel protein 2 Antibody - NBP1-30676 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

Two pore calcium channel protein 2 Antibody - NBP1-86923 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Two pore calcium channel protein 2 Antibody [NBP1-86923] - Staining of human kidney shows strong membranous positivity in cells in glomeruli and subset of cells in tubules.

Two pore calcium channel protein 2 Antibody - NBP1-45234 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TPCN2 antibody produced in rabbit - HPA027080 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TPCN2: <B>Cat. No. HPA027080</B>: Immunohistochemical staining of human prostate shows strong membranous positivity in glandular cells.

TPCN2-Antibody-C-Term - AF3011a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

TPCN2 antibody - orb77572 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of MCF-7 cell lysate using TPCN2 antibody

TPCN2 Antibody (OAEB00169) - OAEB00169 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

TPCN2 Antibody - abx037591 from Abbexa

Host Rabbit
Clonality Polyclonal

TPCN2 (735-747) antibody - AP23140PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-Two Pore Calcium Channel Protein 2 Antibody - AC21-1983 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Two Pore Calcium Channel Protein 2 Antibody (AMCA) - AC21-1983-01 from Abcore

Prices $495.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Two Pore Calcium Channel Protein 2 Antibody (AP) - AC21-1983-02 from Abcore

Prices $505.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-Two Pore Calcium Channel Protein 2 Antibody (APC) - AC21-1983-03 from Abcore

Prices $515.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Search more