KCNK4

Gene Symbol	KCNK4
Entrez Gene	50801
Alt Symbol	K2p4.1, TRAAK, TRAAK1
Species	Human
Gene Type	protein-coding
Description	potassium channel, two pore domain subfamily K, member 4
Other Description	K2P4.1 potassium channel|TWIK-related arachidonic acid-stimulated potassium channel protein|potassium channel subfamily K member 4|potassium channel, subfamily K, member 4|two pore K(+) channel KT4.1|two pore K+ channel KT4.1|two pore potassium channel KT4.1
Swissprots	Q9NYG8 Q96T94 B5TJL1
Accessions	CAC93796 CAD10536 CAD10537 EAW74241 EAW74242 EAW74243 Q9NYG8 AF248242 AAG31731 AF259500 AAK49389 AK296021 BAG58791 AK307135 AK309443 BC033577 BC067791 BC110327 AAI10328 BC160128 AAI60128 DB273064 EU978935 ACH86094 NM_033310 NP_201567 NM_016611 NM_033311
Function	Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity). {ECO:0000250|UniProtKB:G3V8V5, ECO:0000250|UniProtKB:O88454, ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:23341632, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}; Multi-pass membrane protein {ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:23341632, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}.

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• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KCNK4 293 Cell Lysate - 405021 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

KCNK4 Overexpression Lysate (Native) - NBL1-12185 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

KCNK4 Over-expression Lysate Product - GWB-EC88F0 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human KCNK4 Knockdown Stable Cell Line - CSC-DC007985 from Creative biogene Category Cell Line Species Human

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