KCNK4

Gene Symbol KCNK4
Entrez Gene 50801
Alt Symbol K2p4.1, TRAAK, TRAAK1
Species Human
Gene Type protein-coding
Description potassium channel, two pore domain subfamily K, member 4
Other Description K2P4.1 potassium channel|TWIK-related arachidonic acid-stimulated potassium channel protein|potassium channel subfamily K member 4|potassium channel, subfamily K, member 4|two pore K(+) channel KT4.1|two pore K+ channel KT4.1|two pore potassium channel KT4.1
Swissprots Q9NYG8 Q96T94 B5TJL1
Accessions CAC93796 CAD10536 CAD10537 EAW74241 EAW74242 EAW74243 Q9NYG8 AF248242 AAG31731 AF259500 AAK49389 AK296021 BAG58791 AK307135 AK309443 BC033577 BC067791 BC110327 AAI10328 BC160128 AAI60128 DB273064 EU978935 ACH86094 NM_033310 NP_201567 NM_016611 NM_033311
Function Voltage-insensitive potassium channel (PubMed:22282805). Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157). Channel opening is triggered by raising the intracellular pH to basic levels (By similarity). The channel is inactive at 24 degrees Celsius (in vitro); raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity). Plays a role in the perception of pain caused by heat (By similarity). Plays a role in the sensory perception of pain caused by pressure (By similarity). {ECO:0000250|UniProtKB:G3V8V5, ECO:0000250|UniProtKB:O88454, ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:23341632, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}; Multi-pass membrane protein {ECO:0000269|PubMed:22282805, ECO:0000269|PubMed:23341632, ECO:0000269|PubMed:25471887, ECO:0000269|PubMed:25500157}.

TRAAK (A-20) - sc-11326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRAAK (A-20): sc-11326. Western blot analysis of TRAAK expression in IMR-32 whole cell lysate.

TRAAK (N-15) - sc-11323 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRAAK (C-13) - sc-11324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRAAK (C-13): sc-11324. Western blot analysis of TRAAK expression in IMR-32 (A) and Y79 (B) whole cell lysates.

TRAAK (H-45) - sc-50413 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRAAK (H-45): sc-50413. Western blot analysis of TRAAK expression in Jurkat whole cell lysate.

Anti-KCNK4 antibody - ab81367 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KCNK4 antibody (ab81367) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-KCNK4 antibody - ab136984 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KCNK4 antibody (ab136984) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-KCNK4 antibody - C-terminal - ab83726 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-KCNK4 antibody - N-terminal - ab182107 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KCNK4 antibody - N-terminal (ab182107) at 1 µg/ml + Human colorectal tumor lysate at 10 µg

Anti-KCNK4 / TRAAK Antibody (aa314-363) - LS-C292117 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNK4 / TRAAK Antibody (N-Terminus) - LS-C110033 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCNK4 antibody LS-C110033 Western blot of Jurkat lysate.

Anti-KCNK4 / TRAAK Antibody (aa38-87) - LS-C81529 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-KCNK4 / TRAAK Antibody (aa43-92) - LS-C201304 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Colorectal Tumor. KCNK4 antibody dilution 1.0 ug/ml.

Anti-KCNK4 / TRAAK Antibody (aa332-381) - LS-C120232 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HT-29 cells, using KCNK4 Antibody. The lane on the right is treated with the synthesized peptide.

KCNK4 Antibody - NBP1-56144 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: KCNK4 Antibody [NBP1-56144] - Analysis of extracts from HT-29 cells, using KCNK4 Antibody. The lane on the right is treated with the synthesized peptide.

KCNK4 Antibody - NBP1-69621 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: KCNK4 Antibody [NBP1-69621] - This Anti-KCNK4 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1ug/ml.

Anti-KCNK4, (N-terminal) antibody produced in rabbit - SAB2103975 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KCNK4, antibody produced in rabbit: <B>Cat. No. SAB2103975</B>: Immunoblotting analysis of KCNK4 in Jurkat cell lysate with KCNK4 anitbody at 1 μg/mL.

Anti-Potassium Channel K2P4.1 (TRAAK) antibody produced in rabbit - K0265 from Sigma-Aldrich

Prices $255.00, $582.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-K2P4.1 (TRAAK): <B>Cat. No. K0265</B>: Immunohistochemical staining of Rat cerebellum using Anti-K2P4.1 (TRRAK) antibody. <BR/>A. K2P4.1 channel appears in Purkinje neuronal processes (red). <BR/>B. Staining of Purkinje nerve cells with Mouse Anti-Calbindin D28K (a calcium binding protein, green). <BR/>C. Confocal merge of K2P4.1 channel and Calbindin D28K demonstrates the co-localization of these proteins.

Anti-KCNK4 antibody produced in rabbit - AV50179 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV50179</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HepG2

KCNK4 Antibody - N-terminal region (ARP35261_P050) - ARP35261_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNK4 antibody - N-terminal region (ARP35380_P050) - ARP35380_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNK4 antibody - N-terminal region (ARP50179_P050) - ARP50179_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

K2P41-TRAAK-Antibody - AG1103 from Abgent, a WuXi AppTec company

Prices $475.00, $575.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of HEK-293-K2P4.1 transfected cells: 1. Anti-K2P4.1 (TRAAK) antibody (#AG1103), (1:200). 2. Anti-K2P4.1 (TRAAK) antibody, preincubated with the control peptide antigen.

KCNK4 antibody - GTX87726 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-KCNK4 antibody used in Western blot. GTX87726

KCNK4 Antibody (OAAF04031) - OAAF04031 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

KCNK4 Antibody (OAAF06555) - OAAF06555 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more