EXOSC2

Gene Symbol	EXOSC2
Entrez Gene	23404
Alt Symbol	RRP4, Rrp4p, hRrp4p, p7
Species	Human
Gene Type	protein-coding
Description	exosome component 2
Other Description	exosome complex component RRP4|exosome complex exonuclease RRP4|homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4)|homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease|ribosomal RNA-processing protein 4
Swissprots	Q13868 B4DKK6 A3KFL3 Q9NUY4
Accessions	AAB60392 EAW87941 EAW87942 EAW87943 EAW87944 Q13868 AK001916 BAA91977 AK022460 BAB14043 AK090512 BAG52174 AK092727 AK296605 BAG59218 AK303163 BAG64263 AL573310 BC000747 AAH00747 BC128445 AAI28446 BU934039 CB112633 DA813307 DQ892753 ABM83679 EU176744 ABW03545 XM_005272176 XP_005272233 XM_006717022 XP_006717085 XM_006717023 XP_006717086 XM_006717024 XP_006717087 NM_001282708 NP_001269637 NM_001282709 NP_001269638 NM_014285 NP_055100 NR_104230
Function	Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways
Subcellular Location	Cytoplasm. Nucleus, nucleolus. Nucleus.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EXOSC2 / RRP4 ELISA Kit (Sandwich ELISA) - LS-F9346 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Human Exosome Component 2 ELISA Kit - abx151457 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Exosome Component 2, ELISA Kit - MBS072211 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS100146 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

exosome component 2, ELISA Kit - MBS9336140 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS054904 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS051602 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS074942 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS072672 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2, ELISA Kit - MBS061675 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Exosome Component 2 (EXOSC2), ELISA Kit - MBS2022466 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of EXOSC2 is typically less than 0.057ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

ELISA Kit for Exosome Component 2 (EXOSC2) - SEH822Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Exosome Component 2 (EXOSC2) ELISA Kit - EKU03997 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.057 ng/mL Range 0.156-10 ng/mL

Exosome Component 2 (EXOSC2), Human, ELISA Kit - DL-EXOSC2-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human EXOSC2 ELISA Kit - abx571775 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human EXOSC2 ELISA Kit - E013845 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of EXOSC2 is typically less than 0.057ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding t

EXOSC2 ELISA Kit (Human) (OKCD00550) - OKCD00550 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.057 ng/mL Range 0.156-10 ng/mL

EXOSC2 ELISA Kit (Human) (OKDD00259) - OKDD00259 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.061 ng/mL Range 0.156-10 ng/mL

anti-EXOSC2 antibody - ARG57435 from Arigo Biolaboratories Category ELISA Kit

Exosome Component 2 (EXOSC2), ELISA Kit - MBS455208 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.061ng/mL Range 0.156-10ng/mL

Exosome Component 2 (EXOSC2), ELISA Kit - MBS9371085 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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