RASIP1

Gene Symbol	RASIP1
Entrez Gene	54922
Alt Symbol	RAIN
Species	Human
Gene Type	protein-coding
Description	Ras interacting protein 1
Other Description	ras-interacting protein 1
Swissprots	Q6U676 Q5U651
Accessions	EAW52393 EAW52394 Q5U651 AK000408 BAA91145 AK123179 BAG53877 AY378097 AAR24580 BC021860 AAH21860 BC028614 AAH28614 BC042111 AAH42111 BX389914 XM_011527053 XP_011525355 XM_011527054 XP_011525356 XM_011527055 XP_011525357 XR_935837 NM_017805 NP_060275
Function	Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy. {ECO:0000250, ECO:0000269|PubMed:15031288, ECO:0000269|PubMed:22354037}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:15031288}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:15031288}. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Tissue Specificity	Highly expressed in heart. Detected at lower levels in placenta and pancreas. {ECO:0000269|PubMed:15031288}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAIN protein fragment - ab132221 from Abcam Category Protein Source Wheat germ Species Human

RAIN peptide - ab45597 from Abcam Category Peptide

RAIN / RASIP1 Antibody Blocking Peptide - LS-E25743 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAIN / RASIP1 Antibody Blocking Peptide - LS-E8516 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAIN Recombinant Protein - H00054922-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RASIP1-Antibody-Center-Blocking-Peptide - BP6870c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RASIP1/RAIN blocking peptide - GTX41018-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

RASIP1 Blocking Peptide - abx161205 from Abbexa Category Peptide Species Human, Rat

RAIN Peptide - AC21-0572-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

RASIP1 / RAIN - H00054922-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RASIP1 / RAIN - H00054922-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RASIP1 Peptide - 46-272P from ProSci Category Peptide

RASIP1 fusion protein - ag22036 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

RASIP1 fusion protein - ag11963 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RASIP1 fusion protein - Ag11982 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RASIP1 Blocking Peptide - CBP3704 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Rat

Recombinant Human Ras-interacting protein 1(RASIP1) ,partial - CSB-YP722625HU CSB-EP722625HU CSB-BP722625HU CSB-MP722625HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RASIP1/RAIN, Peptide - MBS425991 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

RASIP1 Peptide, Human - M34GP13003H from Creative Peptides Category Peptide Source Synthetic. Species Human

RASIP1 Immunizing peptide - orb17492 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

RASIP1 peptide - orb234579 from Biorbyt Category Peptide Prices $247.00, $536.00 Sizes 1 mg, 5 mg

Ras-interacting protein 1 (RASIP1), partial, Recombinant Protein - MBS1478282 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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