RASIP1

Gene Symbol RASIP1
Entrez Gene 54922
Alt Symbol RAIN
Species Human
Gene Type protein-coding
Description Ras interacting protein 1
Other Description ras-interacting protein 1
Swissprots Q6U676 Q5U651
Accessions EAW52393 EAW52394 Q5U651 AK000408 BAA91145 AK123179 BAG53877 AY378097 AAR24580 BC021860 AAH21860 BC028614 AAH28614 BC042111 AAH42111 BX389914 XM_011527053 XP_011525355 XM_011527054 XP_011525356 XM_011527055 XP_011525357 XR_935837 NM_017805 NP_060275
Function Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy. {ECO:0000250, ECO:0000269|PubMed:15031288, ECO:0000269|PubMed:22354037}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:15031288}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:15031288}. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Tissue Specificity Highly expressed in heart. Detected at lower levels in placenta and pancreas. {ECO:0000269|PubMed:15031288}.

RAIN CRISPR/Cas9 KO Plasmid (h) - sc-407801 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN HDR Plasmid (h) - sc-407801-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN Double Nickase Plasmid (h) - sc-407801-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN Double Nickase Plasmid (h2) - sc-407801-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN CRISPR Activation Plasmid (h) - sc-407801-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN CRISPR Activation Plasmid (h2) - sc-407801-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN Lentiviral Activation Particles (h) - sc-407801-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN Lentiviral Activation Particles (h2) - sc-407801-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAIN siRNA (h) - sc-97326 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAIN shRNA Plasmid (h) - sc-97326-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAIN shRNA (h) Lentiviral Particles - sc-97326-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU029481 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17988 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17988 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01491 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01491

RASIP1 siRNA (Human) - CRJ0326 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RASIP1 - MBS8208572 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RASIP1 (NM_017805.2) - SHH390072 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human RASIP1(NM_017805.2) - SHR166622 from Creative biogene

Category siRNA
Species Reactivities Human

RASIP1 shRNA Plasmid (Human) - CHJ0326 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RASIP1 miRNA 3'UTR clone - MiUTR1H-08648 from Creative biogene

Species Reactivities Human
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