RASIP1

Gene Symbol RASIP1
Entrez Gene 54922
Alt Symbol RAIN
Species Human
Gene Type protein-coding
Description Ras interacting protein 1
Other Description ras-interacting protein 1
Swissprots Q6U676 Q5U651
Accessions EAW52393 EAW52394 Q5U651 AK000408 BAA91145 AK123179 BAG53877 AY378097 AAR24580 BC021860 AAH21860 BC028614 AAH28614 BC042111 AAH42111 BX389914 XM_011527053 XP_011525355 XM_011527054 XP_011525356 XM_011527055 XP_011525357 XR_935837 NM_017805 NP_060275
Function Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy. {ECO:0000250, ECO:0000269|PubMed:15031288, ECO:0000269|PubMed:22354037}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:15031288}. Golgi apparatus, Golgi stack {ECO:0000269|PubMed:15031288}. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Tissue Specificity Highly expressed in heart. Detected at lower levels in placenta and pancreas. {ECO:0000269|PubMed:15031288}.

RAIN (D-14) - sc-240804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RAIN (D-14): sc-240804. Western blot analysis of RAIN expression in K-562 (A), Jurkat (B) and Hep G2 (C) whole cell lysates.

Anti-RAIN antibody - ab129820 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-RAIN antibody (ab129820) at 1/250 dilution + Lung (Mouse) Whole Cell Lysate - normal tissue (ab29297) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-RAIN antibody - ab175595 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RAIN antibody (ab175595) at 1/1000 dilution + K562 cell line lysates at 35 µg

Anti-RAIN antibody - ab169671 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RAIN antibody (ab169671) at 1 µg/mlLane 1 : RAIN-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-RAIN antibody - ab21018 from Abcam

Prices $368.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RAIN antibody - C-terminal - ab134825 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-eEmbedded Human Placenta tissue labelling RAIN with ab134825 at 3.75 µg/ml.

Anti-RAIN / RASIP1 Antibody (aa651-678) - LS-C162460 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with RASIP1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-RAIN / RASIP1 Antibody (aa951-963) IHC-plus™ - LS-B7338 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-RASIP1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7338 concentration 3.75 ug/ml.

RAIN Antibody - H00054922-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

RAIN Antibody - H00054922-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RAIN Antibody [H00054922-B01] - analysis of RASIP1 expression in transfected 293T cell line by RASIP1 MaxPab polyclonal antibody (B01). Lane1: RASIP1 transfected lysate (35.30 KDa). Lane2: Non-transfected lysate.

Anti-RASIP1 antibody produced in mouse - SAB1401733 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-RASIP1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401733</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~34.87 kDa using RASIP1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

ANTI-RASIP1 (CENTER) antibody produced in rabbit - SAB1303024 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

RASIP1-Antibody-Center - AP6870c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RASIP1 Antibody (Center) (Cat. #AP6870c) in K562 cell line lysates (35ug/lane). RASIP1 (arrow) was detected using the purified Pab.

RASIP1 Antibody - middle region (OAAB03981) - OAAB03981 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

RASIP1--RAIN-Antibody-C-Term - AF2413a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Goat Anti-RASIP1 / RAIN Antibody (OAEB00718) - OAEB00718 from Aviva Systems Biology

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RASIP1 Antibody - abx121205 from Abbexa

Host Rabbit
Clonality Polyclonal

RASIP1 Antibody - abx033033 from Abbexa

Host Rabbit
Clonality Polyclonal

RASIP1 / RAIN antibody - 17971-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human heart tissue slide using 17971-1-AP( RASIP1 Antibody) at dilution of 1:50 (under 40x lens)

RASIP1 / RAIN antibody - 26064-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse lung tissue were subjected to SDS PAGE followed by western blot with 26064-1-AP( RASIP1 Antibody) at dilution of 1:300

RASIP1 / RAIN (Center) antibody - AP17706PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of RASIP1 Antibody (Center) (AP17706PU-N) in K562 cell line lysates (35ug/lane). RASIP1 (arrow) was detected using the purified Pab.

RASIP1 / RAIN antibody - H00054922-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of RASIP1 expression in transfected 293T cell line (H00054922-T01) by RASIP1 MaxPab polyclonal antibody.Lane1:RASIP1 tr

RASIP1 / RAIN antibody - H00054922-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of RASIP1 expression in transfected 293T cell line (H00054922-T01) by RASIP1 MaxPab polyclonal antibody. Lane1:RASIP1 transfected lysate(34.87 KDa). Lane2:Non-transfected lysate.

Anti-RAIN Antibody - AC21-0572 from Abcore

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RAIN Antibody (AMCA) - AC21-0572-01 from Abcore

Prices $495.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
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