LAMTOR5

Gene Symbol	LAMTOR5
Entrez Gene	10542
Alt Symbol	HBXIP, XIP
Species	Human
Gene Type	protein-coding
Description	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Other Description	HBV X-interacting protein|HBx-interacting protein|hepatitis B virus x interacting protein|hepatitis B virus x-interacting protein (9.6kD)|late endosomal/lysosomal adaptor and MAPK and MTOR activator 5|ragulator complex protein LAMTOR5
Swissprots	Q6IBD8 O43504
Accessions	EAW56447 O43504 AA443738 AF029890 AAC52032 AK054769 AK056679 BAG51783 AY623819 AAV30683 BC062619 AAH62619 BX092018 CR456866 CAG33147 CR542130 CAG46927 HQ257924 ADR82678 NM_006402 NP_006393
Function	As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. {ECO:0000269|PubMed:12773388, ECO:0000269|PubMed:22980980}.
Subcellular Location	Cytoplasm. Lysosome.
Tissue Specificity	Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HBXIP ELISA Kit (Sandwich ELISA) - LS-F11609 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 1.56-100 ng/ml

Human HBXIP ELISA Kit - abx054609 from Abbexa Category ELISA Kit

Hepatitis B virus X-interacting protein (HBXIP), Human, ELISA Kit - E01H1365 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Hepatitis B virus X-interacting protein, HBXIP, Human, ELISA Kit - E1313h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 ng/mL

hepatitis B virus X interacting protein (HBXIP), ELISA Kit - MBS9311446 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

hepatitis B virus X interacting protein, HBXIP, ELISA Kit - MBS9304522 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0pg/ml. Range 31.2pg/ml-1000pg/ml.

Hepatitis B virus X-interacting protein, ELISA Kit - MBS282323 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bovine HBXIP ELISA Kit (Custom ELISA) - LS-F16850 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 1.56-100 ng/ml

Mouse HBXIP ELISA Kit (Custom ELISA) - LS-F16851 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 1.56-100 ng/ml

Pig HBXIP ELISA Kit (Custom ELISA) - LS-F16849 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 1.56-100 ng/ml

HBXIP - EKH2964 from Nordic BioSite Sensitivity 0.938ng/ml Range 1.56-100ng/ml

HBXIP ELISA Kit (Human) (OKEH00940) - OKEH00940 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.98 ng/mL Range 1.56 - 100 ng/mL

Human HBXIP ELISA Kit - E018342 from Biobool Category ELISA Kit Sensitivity 5.0pg/ml.

Human LAMTOR5 ELISA Kit - E088798 from Biobool Category ELISA Kit

Human Ragulator complex protein LAMTOR5 ELISA Kit - EK3174 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.98ng/mL Range 1.56 ng/mL -100 ng/mL

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9353580 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9365116 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9367235 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9357506 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9366029 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9357801 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9347837 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9368704 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9355276 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Hepatitis B Virus X Interacting Protein (HBXIP), ELISA Kit - MBS9359947 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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