FBXO3

Gene Symbol FBXO3
Entrez Gene 26273
Alt Symbol FBA, FBX3
Species Human
Gene Type protein-coding
Description F-box protein 3
Other Description F-box only protein 3|F-box protein FBX3
Swissprots Q9UK99 B3KY16 Q9H0V2 D3DR05 Q9NUX2 Q86X90
Accessions EAW68186 EAW68187 EAW68188 EAW68189 EAW68190 EAW68191 Q9UK99 AB209039 BAD92276 AF174595 AAF04516 AF176702 AAF03702 AK001943 BAA91991 AK123198 AK128454 BAG54678 AK300721 BAH13334 AK304866 BAG65604 AK316286 BAH14657 AL136625 CAB66560 AL832826 BC017107 BC039291 AAH39291 BC046110 AAH46110 BG716664 EU832324 ACE87581 EU832409 ACE86894 XM_011519980 XP_011518282 XM_011519981 XP_011518283 XM_011519982 XP_011518284 NM_012175 NP_036307 NM_033406 NP_208385
Function Substrate recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53- dependent transactivation. {ECO:0000269|PubMed:18809579}.
Subcellular Location Nucleus. Note=Colocalizes with PML at the peripheries of nuclear bodies.

FBXO3 - MBS1277079 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC046110

Human FBXO3 cDNA clone(NM_033406.2) - CDFG006834 from Creative Biomart

Species Human
Accession NM_033406.2

Human FBXO3 cDNA clone(NM_012175.3) - CDFH006684 from Creative Biomart

Species Human
Accession NM_012175.3

Mouse FBXO3 ORF clone - CDCL107273 from Creative Biomart

Species Human
Accession NM_012175

Mouse FBXO3 ORF clone - CDCL107274 from Creative Biomart

Species Human
Accession NM_012175

Mouse FBXO3 ORF clone - CDCL107275 from Creative Biomart

Species Human
Accession NM_012175

Mouse FBXO3 ORF clone - CDCL107276 from Creative Biomart

Species Human
Accession NM_012175

Human FBXO3 ORF clone - CDCL107277 from Creative Biomart

Species Human
Accession NM_012175

Human FBXO3 ORF clone - CDCL107278 from Creative Biomart

Species Human
Accession NM_012175

Human FBXO3 ORF Clone(NM_012175.3) - CDCL163262 from Creative Biomart

Species Human
Accession NM_012175.3

Human FBXO3 ORF Clone(NM_012175.3) - CDCR295538 from Creative Biomart

Species Human
Accession NM_012175.3

Human FBXO3 ORF Clone(NM_012175.3) - CDCR295539 from Creative Biomart

Species Human
Accession NM_012175.3

Human FBXO3 ORF Clone(NM_012175.3) - CDCR295540 from Creative Biomart

Species Human
Accession NM_012175.3

Human FBXO3 ORF Clone(NM_033406.2) - CDCR313874 from Creative Biomart

Species Human
Accession NM_033406.2

Human FBXO3 ORF Clone(NM_033406.2) - CDCR313875 from Creative Biomart

Species Human
Accession NM_033406.2

Mouse FBXO3 ORF clone (NM_033406.2) - CDCL107273 from Creative biogene

Species Human

Mouse FBXO3 ORF clone (NM_012175.3) - CDCL107275 from Creative biogene

Species Human

Human FBXO3 ORF Clone (BC046110) - CDCS413233 from Creative biogene

Species Human
Accession Q49AF1

Human FBXO3 cDNA Clone(NM_033406.2) - CDFG006834 from Creative biogene

Species Human

Human FBXO3 cDNA Clone(NM_012175.3) - CDFH006684 from Creative biogene

Species Human
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