FBXO3

Gene Symbol FBXO3
Entrez Gene 26273
Alt Symbol FBA, FBX3
Species Human
Gene Type protein-coding
Description F-box protein 3
Other Description F-box only protein 3|F-box protein FBX3
Swissprots Q9UK99 B3KY16 Q9H0V2 D3DR05 Q9NUX2 Q86X90
Accessions EAW68186 EAW68187 EAW68188 EAW68189 EAW68190 EAW68191 Q9UK99 AB209039 BAD92276 AF174595 AAF04516 AF176702 AAF03702 AK001943 BAA91991 AK123198 AK128454 BAG54678 AK300721 BAH13334 AK304866 BAG65604 AK316286 BAH14657 AL136625 CAB66560 AL832826 BC017107 BC039291 AAH39291 BC046110 AAH46110 BG716664 EU832324 ACE87581 EU832409 ACE86894 XM_011519980 XP_011518282 XM_011519981 XP_011518283 XM_011519982 XP_011518284 NM_012175 NP_036307 NM_033406 NP_208385
Function Substrate recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53- dependent transactivation. {ECO:0000269|PubMed:18809579}.
Subcellular Location Nucleus. Note=Colocalizes with PML at the peripheries of nuclear bodies.

FBXO3 CRISPR/Cas9 KO Plasmid (h) - sc-403436 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 HDR Plasmid (h) - sc-403436-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 Double Nickase Plasmid (h) - sc-403436-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 Double Nickase Plasmid (h2) - sc-403436-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 CRISPR Activation Plasmid (h) - sc-403436-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 CRISPR Activation Plasmid (h2) - sc-403436-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 Lentiviral Activation Particles (h) - sc-403436-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 Lentiviral Activation Particles (h2) - sc-403436-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FBXO3 siRNA (h) - sc-96506 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FBXO3 shRNA Plasmid (h) - sc-96506-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FBXO3 shRNA (h) Lentiviral Particles - sc-96506-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU145801 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8546 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07697 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07697

FBXO3 siRNA (Human) - CRH8796 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FBXO3 - MBS8203556 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FBXO3 (NM_012175.3) - SHH293181 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FBXO3(NM_012175.3) - SHH052229 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FBXO3(NM_033406.2) - SHH052283 from Creative biogene

Category siRNA
Species Reactivities Human

Human FBXO3 siRNA - orb269298 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FBXO3 shRNA Plasmid (Human) - CHH8796 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FBXO3 miRNA 3'UTR clone - MiUTR1H-03555 from Creative biogene

Species Reactivities Human

FBXO3 miRNA 3'UTR clone - MiUTR1H-03556 from Creative biogene

Species Reactivities Human
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