FBXO3

Gene Symbol	FBXO3
Entrez Gene	26273
Alt Symbol	FBA, FBX3
Species	Human
Gene Type	protein-coding
Description	F-box protein 3
Other Description	F-box only protein 3|F-box protein FBX3
Swissprots	Q9UK99 B3KY16 Q9H0V2 D3DR05 Q9NUX2 Q86X90
Accessions	EAW68186 EAW68187 EAW68188 EAW68189 EAW68190 EAW68191 Q9UK99 AB209039 BAD92276 AF174595 AAF04516 AF176702 AAF03702 AK001943 BAA91991 AK123198 AK128454 BAG54678 AK300721 BAH13334 AK304866 BAG65604 AK316286 BAH14657 AL136625 CAB66560 AL832826 BC017107 BC039291 AAH39291 BC046110 AAH46110 BG716664 EU832324 ACE87581 EU832409 ACE86894 XM_011519980 XP_011518282 XM_011519981 XP_011518283 XM_011519982 XP_011518284 NM_012175 NP_036307 NM_033406 NP_208385
Function	Substrate recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53- dependent transactivation. {ECO:0000269|PubMed:18809579}.
Subcellular Location	Nucleus. Note=Colocalizes with PML at the peripheries of nuclear bodies.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human F Box G - Domain 3 full length protein - ab161962 from Abcam Category Protein Source Wheat germ Species Human

Human F Box G - Domain 3 full length protein - ab161963 from Abcam Category Protein Source Wheat germ Species Human

Human F Box G - Domain 3 protein fragment - ab161964 from Abcam Category Protein Source Wheat germ Species Human

FBXO3 Antibody Blocking Peptide - LS-E15877 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXO3 Antibody Blocking Peptide - LS-E9997 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FBXO3 Protein - H00026273-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FBXO3 Protein - H00026273-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FBXO3 Protein - H00026273-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FBXO3-Antibody-C-term-Blocking-Peptide - BP9195b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBXO3 Blocking Peptide - 33R-6651 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXO3 Blocking Peptide - 33R-1890 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXO3 - H00026273-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FBXO3 - H00026273-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FBXO3 - H00026273-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

FBXO3 - H00026273-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FBXO3 - H00026273-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FBXO3 - H00026273-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FBXO3 - H00026273-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FBXO3 fusion protein - Ag12071 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

FBXO3 fusion protein - ag11758 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human FBXO3, His-tagged - FBXO3-12794H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Aldolase A, Fructose Bisphosphate (ALDOA) - RPA642Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human F-box only protein 3(FBXO3) - CSB-YP892132HU CSB-EP892132HU CSB-BP892132HU CSB-MP892132HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBXO3 (transcript variant 1) - TP308494 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

FBXO3 Peptide, Human - M34GP05597H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more