DHRS4

Gene Symbol	DHRS4
Entrez Gene	10901
Alt Symbol	CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2
Species	Human
Gene Type	protein-coding
Description	dehydrogenase/reductase (SDR family) member 4
Other Description	NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase|NADPH-dependent retinol dehydrogenase/reductase|dehydrogenase/reductase (SDR family) member 4 like 2A|dehydrogenase/reductase SDR family member 4|peroxisomal short-chain alcohol dehydrogenase|short chain dehydrogenase/reductase family 25C member 2|short chain dehydrogenase/reductase family 25C, member 1|short chain dehydrogenase/reductase family 25C, member 2|short-chain dehydrogenase/reductase family member 4
Swissprots	Q9NV08 Q2LE81 B2RB10 Q20CR0 Q8TD03 Q6UWU3 E2QRL8 D3YTB8 Q9BTZ2 Q9H3N5 Q71UQ6 Q2LC19 Q6E0Y1 Q58IU4 O95162 B7WNS9
Accessions	Q9BTZ2 AA293161 AA639837 AB045131 BAB18775 AF044127 AAD02292 AF064256 AAQ13444 AK001870 BAA91953 AK301201 BAH13431 AK308436 AK314448 BAG37057 AY071856 AAL61824 AY358638 AAQ89001 AY616182 AAT70757 BC003019 AAH03019 BP366505 BQ030242 BU529016 CA438339 CD674505 DQ325464 ABC61320 DQ338571 ABC61321 DQ344810 ABD75823 XM_006720005 XP_006720068 XM_011536366 XP_011534668 NM_001282987 NP_001269916 NM_001282988 NP_001269917 NM_001282989 NP_001269918 NM_001282990 NP_001269919 NM_001282991 NP_001269920 NM_021004 NP_066284
Function	Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity). {ECO:0000250}.
Subcellular Location	Peroxisome {ECO:0000269|PubMed:10333503}. Note=Isoform 1 is peroxisomal, while isoform 4 is not.
Tissue Specificity	Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
Top Pathways	Peroxisome, Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DHRS4 (L-13) - sc-131492 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-DHRS4 antibody - ab92713 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DHRS4 antibody - ab68095 from Abcam Prices $370.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-DHRS4 antibody - ab88703 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-DHRS4 / PSCD Antibody - LS-C307244 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-DHRS4 / PSCD Antibody (aa53-102) - LS-C151478 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DHRS4 / PSCD Antibody (aa51-100) - LS-C170368 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DHRS4 / PSCD Antibody (aa191-240) - LS-C119899 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

DHRS4 Antibody - NBP1-83790 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

DHRS4 Antibody - H00010901-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

DHRS4 Antibody - H00010901-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

DHRS4 Polyclonal Antibody - bs-8264R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DHRS4 antibody produced in mouse - SAB1400408 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-DHRS4 antibody produced in rabbit - HPA023972 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

DHRS4 antibody - N-terminal region (ARP62272_P050) - ARP62272_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

DHRS4 Antibody (OAAF03561) - OAAF03561 from Aviva Systems Biology Prices $289.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

DHRS4 antibody - 70R-16824 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

DHRS4 antibody - orb194546 from Biorbyt Prices $417.00, $536.00 Sizes 50 μl, 100 μl Host Rabbit Clonality Polyclonal

DHRS2 antibody - 70R-8533 from Fitzgerald Prices $345.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

DHRS4 Antibody - abx014421 from Abbexa Host Rabbit Clonality Polyclonal

DHRS4 antibody - 15279-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

DHRS4 antibody - H00010901-B01 from Acris Antibodies Prices $360.00 Sizes 50 µl Host Mouse Clonality Polyclonal

DHRS4 antibody - H00010901-B01P from Acris Antibodies Prices $360.00 Sizes 50 µg Host Mouse Clonality Polyclonal

DHRS4 antibody - 15279-1-AP from Proteintech Group Prices $279.00 Sizes con: 21 μg/150μl Host Rabbit Clonality Polyclonal

Anti-DHRS4 antibody - STJ92714 from St John's Laboratory Ltd Host Rabbit Clonality Polyclonal

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