DHRS4

Gene Symbol	DHRS4
Entrez Gene	10901
Alt Symbol	CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2
Species	Human
Gene Type	protein-coding
Description	dehydrogenase/reductase (SDR family) member 4
Other Description	NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase|NADPH-dependent retinol dehydrogenase/reductase|dehydrogenase/reductase (SDR family) member 4 like 2A|dehydrogenase/reductase SDR family member 4|peroxisomal short-chain alcohol dehydrogenase|short chain dehydrogenase/reductase family 25C member 2|short chain dehydrogenase/reductase family 25C, member 1|short chain dehydrogenase/reductase family 25C, member 2|short-chain dehydrogenase/reductase family member 4
Swissprots	Q9NV08 Q2LE81 B2RB10 Q20CR0 Q8TD03 Q6UWU3 E2QRL8 D3YTB8 Q9BTZ2 Q9H3N5 Q71UQ6 Q2LC19 Q6E0Y1 Q58IU4 O95162 B7WNS9
Accessions	Q9BTZ2 AA293161 AA639837 AB045131 BAB18775 AF044127 AAD02292 AF064256 AAQ13444 AK001870 BAA91953 AK301201 BAH13431 AK308436 AK314448 BAG37057 AY071856 AAL61824 AY358638 AAQ89001 AY616182 AAT70757 BC003019 AAH03019 BP366505 BQ030242 BU529016 CA438339 CD674505 DQ325464 ABC61320 DQ338571 ABC61321 DQ344810 ABD75823 XM_006720005 XP_006720068 XM_011536366 XP_011534668 NM_001282987 NP_001269916 NM_001282988 NP_001269917 NM_001282989 NP_001269918 NM_001282990 NP_001269919 NM_001282991 NP_001269920 NM_021004 NP_066284
Function	Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity). {ECO:0000250}.
Subcellular Location	Peroxisome {ECO:0000269|PubMed:10333503}. Note=Isoform 1 is peroxisomal, while isoform 4 is not.
Tissue Specificity	Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
Top Pathways	Peroxisome, Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DHRS4 full length protein - ab116155 from Abcam Category Protein Source E. coli Species Human

DHRS4 / PSCD Antibody Blocking Peptide - LS-E22756 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHRS4 / PSCD Antibody Blocking Peptide - LS-E22755 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DHRS4 Recombinant Protein - H00010901-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human DHRS4 Protein - NBP1-78825 from Novus Biologicals Category Protein Prices $269.00 Sizes 10 µg Source E. coli Species Human

DHRS4-Antibody-N-term-Blocking-peptide - BP12335a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DHRS4-Antibody-Center-Blocking-peptide - BP13614c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human DHRS4 protein - orb168231 from Biorbyt Category Protein Prices $230.00, $442.00, $1,828.00 Sizes 1 μg, 5 μg, 50 μg Source E. coli Species Human

DHRS4 protein (His tag) - 80R-2068 from Fitzgerald Category Protein Prices $270.00 Sizes 10 µg Source E.coli

DHRS4 (1-278, His-tag) - AR50151PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

DHRS4 (1-278, His-tag) - AR50151PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

DHRS4 - H00010901-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

DHRS4 - H00010901-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

DHRS4 - H00010901-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

DHRS4, 1-278aa, Human, His tag, E.coli - 01-P1326 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

DHRS4 fusion protein - Ag7398 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

DHRS4 fusion protein - ag7842 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

DHRS4 Human - ENPS-214 from NeoScientific Category Protein Prices $65.00, $169.00, $1,430.00 Sizes 1 µg, 5 µg, 50 µg Source Escherichia Coli. Species Human

Recombinant Human Dehydrogenase/Reductase Member 4 Enzyme - BP002765-ENZ-207 from Syd Labs Category Protein Prices $160.00, $1,100.00 Sizes 5 µg, 50 µg Source E. coli-derived. Species Human

DHRS4, 1-278aa, Recombinant Protein - GWB-P0712J from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

Recombinant Human Dehydrogenase/Reductase (SDR family) Member 4, His-tagged - DHRS4-1326H from Creative Biomart Category Protein

Recombinant Human DHRS4, His-tagged - DHRS4-26686TH from Creative Biomart Category Protein Source E. coli

Recombinant Human DHRS4, GST-tagged - DHRS4-11976H from Creative Biomart Category Protein Source E.coli Species Human

DHRS4 1-278aa - CMB-1159 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 10.00 µg, 50.00 µg Source E.coli Species Human

Recombinant Human Dehydrogenase/reductase SDR family member 4(DHRS4) - CSB-YP861137HU CSB-EP861137HU CSB-BP861137HU CSB-MP861137HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more