Gene Symbol | GSTO1 |
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Entrez Gene | 9446 |
Alt Symbol | GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase omega 1 |
Other Description | MMA(V) reductase|S-(Phenacyl)glutathione reductase|epididymis secretory protein Li 21|glutathione S-transferase omega 1-1|glutathione S-transferase omega-1|glutathione-S-transferase like|glutathione-dependent dehydroascorbate reductase|monomethylarsonic acid reductase |
Swissprots | F5H7H0 P78417 Q5TA03 Q7Z3T2 D3DRA3 |
Accessions | AAV68046 EAW49601 EAW49602 EAW49603 EAW49604 P78417 AF212303 AAF73376 AK313680 BAG36430 BC000127 AAH00127 BX537431 CAD97673 CA431506 CF130513 CN283947 DB501888 DT220068 EU794619 ACJ13673 U90313 AAB70109 NM_001191002 NP_001177931 NM_001191003 NP_001177932 NM_004832 NP_004823 |
Function | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179, ECO:0000269|PubMed:17226937, ECO:0000269|PubMed:18028863, ECO:0000269|PubMed:21106529}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:11511179}. |
Tissue Specificity | Ubiquitous. Highest expression in liver, pancreas, skeletal muscle, spleen, thymus, colon, blood leukocyte and heart. Lowest expression in brain, placenta and lung. {ECO:0000269|PubMed:10783391}. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
Human glutathione S transferase Omega 1 (mutated ) full length protein - ab82954 from Abcam
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Human glutathione S transferase Omega 1 full length protein - ab40259 from Abcam
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Human glutathione S transferase Omega 1 full length protein - ab83020 from Abcam
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Human glutathione S transferase Omega 1 full length protein - ab83021 from Abcam
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Human glutathione S transferase Omega 1 full length protein - ab83166 from Abcam
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GSTO1 Antibody Blocking Peptide - LS-E7210 from LifeSpan Bioscience
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GSTO1 Partial Recombinant Protein - H00009446-Q01 from Novus Biologicals
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GSTO1 Recombinant Protein - H00009446-P01 from Novus Biologicals
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Recombinant Human GSTO1 Protein - NBP1-37093 from Novus Biologicals
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GSTO1-Antibody-Center-Blocking-Peptide - BP2930c from Abgent, a WuXi AppTec company
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GSTO1 Human Mutant Protein (OPPA01857) - OPPA01857 from Aviva Systems Biology
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GSTO1 Protein (OPPA01944) - OPPA01944 from Aviva Systems Biology
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Human GSTO1 protein - orb90133 from Biorbyt
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Human GSTo1 Protein - abx066853 from Abbexa
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Human GSTO1 Protein - abx060048 from Abbexa
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GSTO1 (1-241) - AR09373PU-L from Acris Antibodies
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GSTO1 (1-241) - AR09373PU-N from Acris Antibodies
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GSTO1 - H00009446-P01-10 from Acris Antibodies
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GSTO1 - H00009446-P01-25 from Acris Antibodies
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GSTO1 - H00009446-Q01-10 from Acris Antibodies
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GSTO1 - H00009446-Q01-25 from Acris Antibodies
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Glutathione S-Transferase Omega 1, Human Recombinant - 228-10588-1 from RayBiotech
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Recombinant Human GSTO1 - 228-10588-2 from RayBiotech
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Recombinant Human GSTO1 - 228-10588-3 from RayBiotech
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Glutathione S-Transferase Omega 1 Mutant, Human Recombinant - 228-10589-1 from RayBiotech
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