Gene Symbol | GSTO1 |
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Entrez Gene | 9446 |
Alt Symbol | GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase omega 1 |
Other Description | MMA(V) reductase|S-(Phenacyl)glutathione reductase|epididymis secretory protein Li 21|glutathione S-transferase omega 1-1|glutathione S-transferase omega-1|glutathione-S-transferase like|glutathione-dependent dehydroascorbate reductase|monomethylarsonic acid reductase |
Swissprots | F5H7H0 P78417 Q5TA03 Q7Z3T2 D3DRA3 |
Accessions | AAV68046 EAW49601 EAW49602 EAW49603 EAW49604 P78417 AF212303 AAF73376 AK313680 BAG36430 BC000127 AAH00127 BX537431 CAD97673 CA431506 CF130513 CN283947 DB501888 DT220068 EU794619 ACJ13673 U90313 AAB70109 NM_001191002 NP_001177931 NM_001191003 NP_001177932 NM_004832 NP_004823 |
Function | Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. {ECO:0000269|PubMed:10783391, ECO:0000269|PubMed:11511179, ECO:0000269|PubMed:17226937, ECO:0000269|PubMed:18028863, ECO:0000269|PubMed:21106529}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:11511179}. |
Tissue Specificity | Ubiquitous. Highest expression in liver, pancreas, skeletal muscle, spleen, thymus, colon, blood leukocyte and heart. Lowest expression in brain, placenta and lung. {ECO:0000269|PubMed:10783391}. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
GSTO1 (6) - sc-130318 from Santa Cruz Biotechnology
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GSTO1 (E-12) - sc-74935 from Santa Cruz Biotechnology
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GSTO1 (21) - sc-130317 from Santa Cruz Biotechnology
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GSTO1/2 (D-12) - sc-166040 from Santa Cruz Biotechnology
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GSTO1/2 (D-8) - sc-166039 from Santa Cruz Biotechnology
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GSTO1/2 (FL-241) - sc-98560 from Santa Cruz Biotechnology
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GSTO1/2 (H-12) - sc-166121 from Santa Cruz Biotechnology
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Anti-glutathione S transferase Omega 1 antibody - ab88604 from Abcam
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Anti-glutathione S transferase Omega 1 antibody - ab174253 from Abcam
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Anti-glutathione S transferase Omega 1 antibody - ab56550 from Abcam
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Anti-glutathione S transferase Omega 1 antibody - ab96586 from Abcam
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Anti-glutathione S transferase Omega 1 antibody [EPR8370(B)] - ab129106 from Abcam
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Anti-glutathione S transferase Omega 1 antibody [EPR8371(B)] - ab131262 from Abcam
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Anti-glutathione S transferase Omega 1 antibody - C-terminal - ab190308 from Abcam
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Anti-GSTO1 Antibody (aa3-240, Biotin) - LS-C300937 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (aa3-240, FITC) - LS-C305576 from LifeSpan Bioscience
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Anti-GSTO1 Antibody - LS-C178769 from LifeSpan Bioscience
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Anti-GSTO1 Antibody - LS-C308140 from LifeSpan Bioscience
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Anti-GSTO1 Antibody - LS-C310541 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (clone 1B6) - LS-C139239 from LifeSpan Bioscience
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Anti-GSTO1 Antibody - LS-C178768 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (aa3-240) - LS-C294270 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (aa207-221) - LS-C305871 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (Internal, clone EPR8371(B)) - LS-C154595 from LifeSpan Bioscience
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Anti-GSTO1 Antibody (Internal, clone EPR8370(B)) - LS-C154391 from LifeSpan Bioscience
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