CDNF

Gene Symbol	CDNF
Entrez Gene	441549
Alt Symbol	ARMETL1
Species	Human
Gene Type	protein-coding
Description	cerebral dopamine neurotrophic factor
Other Description	ARMET-like protein 1\|arginine-rich, mutated in early stage tumors-like 1\|conserved dopamine neurotrophic factor
Swissprots	B4DVW3 Q49AH0 A2RUU0
Accessions	EAW86263 EAW86264 EAW86265 EAW86266 Q49AH0 AK131035 AV657190 BC037872 AAH37872 BC133042 AAI33043 BC133044 AAI33045 BC144619 BG213461 BQ025443 CN311321 XM_011519488 XP_011517790 XM_011519489 XP_011517791 NM_001029954 NP_001025125
Function	Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). {ECO:0000250}.
Subcellular Location	Secreted {ECO:0000269\|PubMed:17611540, ECO:0000269\|PubMed:18561914}.
Tissue Specificity	Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. {ECO:0000269\|PubMed:17611540}.

CDNF (T-13) - sc-162668 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-ARMETL1 antibody - ab122871 from Abcam

Prices	$443.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ab122871 at 1/20 dilution staining ARMETL1 in paraffin-embedded Human liver tissue by Immunohistochemistry.

Anti-ARMETL1 antibody - ab130848 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ARMETL1 antibody (ab130848) at 1/6000 dilution + Recombinant ARMETL1 expressed into the supernatant of CHO cell culture medium

Anti-ARMETL1 antibody - N-terminal - ab136329 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-ARMETL1 antibody - N-terminal (ab136329) at 1 µg/ml + HeLa cell lysate at 10 µg

Anti-CDNF / ARMETL1 Antibody (aa27-187, clone 12K60) - LS-C182810 from LifeSpan Bioscience

Prices	$485.00
Sizes	100 µg
Host	Rat
Clonality	Monoclonal
Clone	12K60

Anti-CDNF / ARMETL1 Antibody - LS-C293289 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody - LS-C293293 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa33-187, Biotin) - LS-C298572 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa33-187, Biotin) - LS-C299664 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (Biotin) - LS-C299986 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (FITC) - LS-C304162 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (FITC) - LS-C305168 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa33-187, FITC) - LS-C304400 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa33-187) - LS-C293290 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of recombinant CDNF / ARMETL1.

Anti-CDNF / ARMETL1 Antibody (aa33-187) - LS-C293288 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa33-187, FITC) - LS-C305169 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (aa52-101) - LS-C169762 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (Biotin) - LS-C305815 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 Antibody (N-Terminus) - LS-C34749 from LifeSpan Bioscience

Prices	$345.00, $1,035.00
Sizes	100 µg, 500 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence of CDNF in Human Brain cells with CDNF antibody at 20 ug/ml.

Anti-CDNF / ARMETL1 Antibody (C-Terminus) IHC-plus™ - LS-B2731 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDNF / ARMETL1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2731 concentration 5 ug/ml.

CDNF Antibody [Unconjugated] - AF5097 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

CDNF was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using 10 µg/mL Goat Anti-Human CDNF Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5097) overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

CDNF Antibody - NBP1-76834 from Novus Biologicals

Prices	$369.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: CDNF Antibody [NBP1-76834] - Mouse brain tissue lysate with CDNF antibody at (A) 2 and (B) 4 ug/ml.

CDNF Antibody - NBP1-76835 from Novus Biologicals

Prices	$329.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: CDNF Antibody [NBP1-76835] - A-20 cell lysate in (A) the absence and (B) the presence of blocking peptide with CDNF antibody at 1 ug/ml.

CDNF Antibody - NBP1-88994 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CDNF Antibody [NBP1-88994] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

CDNF Antibody - 26150002 from Novus Biologicals

Prices	$369.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

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