Gene Symbol | CPT1A |
---|---|
Entrez Gene | 1374 |
Alt Symbol | CPT1, CPT1-L, L-CPT1 |
Species | Human |
Gene Type | protein-coding |
Description | carnitine palmitoyltransferase 1A (liver) |
Other Description | CPT I|CPTI-L|carnitine O-palmitoyltransferase 1, liver isoform|carnitine O-palmitoyltransferase I, liver isoform|carnitine palmitoyltransferase I, liver |
Swissprots | Q9BWK0 Q8TCU0 P50416 |
Accessions | CAD12625 CAD59673 EAW74721 EAW74722 P50416 AA632225 AJ420378 CAD12576 AK025307 AK172798 AK309464 AK314301 BAG36955 BC000185 AAH00185 BT009791 AAP88793 DB063502 L39211 AAC41748 X83113 XM_005273762 XP_005273819 XM_005273763 XP_005273820 NM_001031847 NP_001027017 NM_001876 NP_001867 |
Function | Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000269|PubMed:11350182, ECO:0000269|PubMed:14517221}; Multi- pass membrane protein {ECO:0000269|PubMed:11350182, ECO:0000269|PubMed:14517221}. |
Tissue Specificity | Strong expression in kidney and heart, and lower in liver and skeletal muscle. |
Top Pathways | Adipocytokine signaling pathway, PPAR signaling pathway, AMPK signaling pathway, Glucagon signaling pathway, Fatty acid degradation |
Human CPT1A full length protein - ab132553 from Abcam
|
||||||||||
Recombinant CPT1A (human) - ab128569 from Abcam
|
||||||||||
Human CPT1A protein fragment - ab114450 from Abcam
|
||||||||||
CPT1A Antibody Blocking Peptide - LS-E3482 from LifeSpan Bioscience
|
||||||||||
CPT1A Antibody Blocking Peptide - LS-E26168 from LifeSpan Bioscience
|
||||||||||
CPT1A Antibody Blocking Peptide - LS-E16450 from LifeSpan Bioscience
|
||||||||||
CPT1A Antibody Blocking Peptide - LS-E26874 from LifeSpan Bioscience
|
||||||||||
Recombinant Human CPT1A Protein - H00001374-P01 from Novus Biologicals
|
||||||||||
CPT1A Partial Recombinant Protein - H00001374-Q01 from Novus Biologicals
|
||||||||||
CPT1A Peptide - P1141 from Novus Biologicals
|
||||||||||
CPT1A-Antibody-C-term-Blocking-Peptide - BP14666b from Abgent, a WuXi AppTec company
|
||||||||||
CPT1A-Antibody-C-term-Blocking-Peptide - BP2524b from Abgent, a WuXi AppTec company
|
||||||||||
CPT1A blocking peptide - GTX89237-PEP from GeneTex
|
||||||||||
CPT1A Blocking Peptide - 33R-5461 from Fitzgerald
|
||||||||||
Human CPT1A Protein - abx065733 from Abbexa
|
||||||||||
CPT1A Peptide - AC21-0998-P from Abcore
|
||||||||||
CPT1A / CPT1-L - H00001374-P01 from Acris Antibodies
|
||||||||||
CPT1A / CPT1-L - H00001374-P01-10 from Acris Antibodies
|
||||||||||
CPT1A / CPT1-L - H00001374-Q01-10 from Acris Antibodies
|
||||||||||
CPT1A / CPT1-L - H00001374-Q01-25 from Acris Antibodies
|
||||||||||
Carnitine Palmitoyltransferase 1A, Liver (CPT1A), Human - 20-9061 from ARP American Research Products
|
||||||||||
CPT1A Peptide - 45-426P from ProSci
|
||||||||||
CPT1A fusion protein - Ag7745 from Proteintech Group
|
||||||||||
CPT1A fusion protein - Ag7202 from Proteintech Group
|
||||||||||
Recombinant Human CPT1A - CPT1A-26794TH from Creative Biomart
|