PUM1

Gene Symbol PUM1
Entrez Gene 9698
Alt Symbol HSPUM, PUMH, PUMH1, PUML1
Species Human
Gene Type protein-coding
Description pumilio RNA-binding family member 1
Other Description pumilio homolog 1|pumilio-1
Swissprots E9PCJ0 Q5VXY7 Q53HH5 A8K6W4 D3DPN3 Q9HAN1 B4DG92 Q14671
Accessions EAX07630 EAX07631 EAX07632 EAX07633 EAX07634 Q14671 AF315592 AAG31807 AK056662 AK096476 BAG53299 AK222605 BAD96325 AK291779 BAF84468 AK294477 BAG57703 AK300457 BAG62177 AL699026 BC013398 AAH13398 BX647437 CN402209 D43951 BAA07895 JF432347 ADZ15564 NM_001020658 NP_001018494 NM_014676 NP_055491
Function Sequence-specific RNA-binding protein that negatively regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE). Capable of deadenylation-dependent and -independent modes of repression. May be required to support proliferation and self-renewal of stem cells. {ECO:0000269|PubMed:21397187, ECO:0000269|PubMed:22955276}.
Subcellular Location Cytoplasm {ECO:0000305}.
Tissue Specificity Expressed in brain, heart, kidney, muscle, intestine and stomach. Not expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested. {ECO:0000269|PubMed:12459267}.

Pumilio 1 Antibody - 12322 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Pumilio 1 Antibody.

Pumilio 1 (H-140) - sc-135049 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Pumilio 1 (H-140): sc-135049. Western blot analysis of Pumilio 1 expression in HeLa (A), NTERA-2 cl.D1 (B), F9 (C) and K-562 (D) whole cell lysates.

Pumilio 1 (N-19) - sc-65187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Pumilio 1 (S-19) - sc-65188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pumilio 1 (S-19): sc-65188. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells.

Pumilio 1 (W-20) - sc-65189 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pumilio 1 (W-20): sc-65189. Western blot analysis of Pumilio 1 expression in HEK293 (A) and HeLa (B) whole cell lysates.

Anti-Pumilio 1 antibody - ab80216 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Pumilio 1 antibody (ab80216) at 1/50 dilutionLane 1 : Non-transfected 293 cell lysatesLane 2 : 293 cell lysates transiently transfected with the Pumilio 1 geneLysates/proteins at 2 µg per lane.

Anti-Pumilio 1 antibody [EPR3795] - ab92545 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3795
All lanes : Anti-Pumilio 1 antibody [EPR3795] (ab92545) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysates Lysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Pumilio 1 antibody - N-terminal - ab75943 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Pumilio 1 antibody - N-terminal (ab75943) at 1/50 dilutionLane 1 : 293 cell lysates, non-transfected Lane 2 : 293 cell lysates, transiently transfected with the PUM1 gene Lysates/proteins at 2 µg per lane.

Anti-PUM1 Antibody - LS-C93491 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Goat
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, AP) - LS-C220469 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, APC) - LS-C220470 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, Biotin) - LS-C220471 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, Azide-free, HRP) - LS-C220473 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, PE) - LS-C220474 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (Tyr83, FITC) - LS-C220472 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (aa225-275) - LS-C56967 from LifeSpan Bioscience

Prices $345.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Detection of human and mouse PUM1 in RIPA extracts of HeLa and 3T3 cells treated with calf alkaline phosphatase or left untreated by Western blotting with Goat anti- Human PUM1 (LS-C56967).

Anti-PUM1 Antibody (N-Terminus, AP) - LS-C220475 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus, APC) - LS-C220476 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus, Biotin) - LS-C220477 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus, FITC) - LS-C220478 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus, Azide-free, HRP) - LS-C220479 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus, PE) - LS-C220480 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (N-Terminus) - LS-C328407 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (aa1-50) - LS-C289307 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PUM1 Antibody (aa200-250) - LS-C289308 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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