Gene Symbol | ANAPC1 |
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Entrez Gene | 64682 |
Alt Symbol | APC1, MCPR, TSG24 |
Species | Human |
Gene Type | protein-coding |
Description | anaphase promoting complex subunit 1 |
Other Description | anaphase-promoting complex 1 (meiotic checkpoint regulator)|anaphase-promoting complex subunit 1|cyclosome subunit 1|mitotic checkpoint regulator|testis-specific gene 24 protein |
Swissprots | Q9BSE6 Q9H8D0 Q2M3H8 Q9H1A4 |
Accessions | EAW52095 Q9H1A4 AI421643 AJ278357 CAC19484 AK023807 BAB14687 AK094527 AL832013 BC005089 AAH05089 BC104902 AAI04903 BC104904 AAI04905 BX282336 DQ786207 DQ786300 XM_011511633 XP_011509935 XM_011511634 XP_011509936 XM_011511635 XP_011509937 XM_011511636 XP_011509938 XM_011511637 XP_011509939 NM_022662 NP_073153 |
Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}. |
Top Pathways | Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection |
Human Apc1 protein fragment - ab163855 from Abcam
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ANAPC1 / APC1 Antibody Blocking Peptide - LS-E30910 from LifeSpan Bioscience
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Recombinant Human Apc1 Protein - H00064682-Q01 from Novus Biologicals
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Apc1 Blocking Peptide - NBP1-77375PEP from Novus Biologicals
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ANAPC1-Antibody-Center-Blocking-Peptide - BP10459c from Abgent, a WuXi AppTec company
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ANAPC1-Antibody-N-term-Blocking-Peptide - BP10452a from Abgent, a WuXi AppTec company
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ANAPC1 Blocking Peptide - abx063953 from Abbexa
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APC1 / ANAPC1 - H00064682-Q01-10 from Acris Antibodies
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APC1 / ANAPC1 - H00064682-Q01-25 from Acris Antibodies
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APC1 / ANAPC1 Control Peptide - AP30057CP-N from Acris Antibodies
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APC1 Peptide - 5717P from ProSci
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ANAPC1 fusion protein - ag13399 from Proteintech Group
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ANAPC1 fusion protein - ag13392 from Proteintech Group
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Recombinant Human ANAPC1, His-tagged - ANAPC1-9633H from Creative Biomart
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ANAPC1 Blocking Peptide - CBP2759 from Cohesion Biosciences
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APC1 (E684) Peptide - BS1611P from Bioworld Technology
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Recombinant Human Anaphase-promoting complex subunit 1(ANAPC1) ,partial - CSB-YP867126HU CSB-EP867126HU CSB-BP867126HU CSB-MP867126HU from Cusabio
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Anaphase-promoting complex subunit 1(ANAPC1) ,partial, Recombinant Protein - MBS1417044 from MyBioSource
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Apc1 Recombinant Protein Antigen - NBP2-37901PEP from Novus Biologicals
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Apc1 Recombinant Protein Antigen - NBP2-37880PEP from Novus Biologicals
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Apc1 Recombinant Protein Antigen - NBP1-90141PEP from Novus Biologicals
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ANAPC1 Peptide, Human - M34GP00578H from Creative Peptides
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ANAPC1 (pS688) Blocking Peptide - CBP5307 from Cohesion Biosciences
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ANAPC1 peptide - orb382164 from Biorbyt
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