ANAPC1

Gene Symbol	ANAPC1
Entrez Gene	64682
Alt Symbol	APC1, MCPR, TSG24
Species	Human
Gene Type	protein-coding
Description	anaphase promoting complex subunit 1
Other Description	anaphase-promoting complex 1 (meiotic checkpoint regulator)|anaphase-promoting complex subunit 1|cyclosome subunit 1|mitotic checkpoint regulator|testis-specific gene 24 protein
Swissprots	Q9BSE6 Q9H8D0 Q2M3H8 Q9H1A4
Accessions	EAW52095 Q9H1A4 AI421643 AJ278357 CAC19484 AK023807 BAB14687 AK094527 AL832013 BC005089 AAH05089 BC104902 AAI04903 BC104904 AAI04905 BX282336 DQ786207 DQ786300 XM_011511633 XP_011509935 XM_011511634 XP_011509936 XM_011511635 XP_011509937 XM_011511636 XP_011509938 XM_011511637 XP_011509939 NM_022662 NP_073153
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® APC1 siRNA II - 13506 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

SignalSilence ® APC1 siRNA I - 13441 from Cell Signaling Technology Category siRNA Prices $249.00 Sizes 300 µl (3 nmol)

APC1 CRISPR/Cas9 KO Plasmid (h) - sc-405103 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 HDR Plasmid (h) - sc-405103-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 Double Nickase Plasmid (h) - sc-405103-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 Double Nickase Plasmid (h2) - sc-405103-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 CRISPR Activation Plasmid (h) - sc-405103-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 CRISPR Activation Plasmid (h2) - sc-405103-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 Lentiviral Activation Particles (h) - sc-405103-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 Lentiviral Activation Particles (h2) - sc-405103-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APC1 siRNA (h) - sc-37524 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APC1 shRNA Plasmid (h) - sc-37524-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APC1 shRNA (h) Lentiviral Particles - sc-37524-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU029991 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3135 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3135 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01270 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr01270

ANAPC1 siRNA (Human) - CRJ2048 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ANAPC1 - MBS8213956 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ANAPC1 (NM_022662.3) - SHH236062 from Creative biogene Category siRNA Species Reactivities Human

Human ANAPC1 siRNA - orb272549 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ANAPC1 shRNA Plasmid (Human) - CHJ2048 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ANAPC1 miRNA 3'UTR clone - MiUTR3H-10023 from Creative biogene Species Reactivities Human

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