Gene Symbol | ATAD2 |
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Entrez Gene | 29028 |
Alt Symbol | ANCCA, CT137, PRO2000 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 2 |
Other Description | AAA nuclear coregulator cancer-associated protein|ATPase family AAA domain-containing protein 2 |
Swissprots | Q8N890 Q68CQ0 Q6PJV6 Q658P2 Q6PL18 Q9UHS5 Q14CR1 |
Accessions | EAW92033 EAW92034 EAW92035 EAW92036 Q6PL18 AF118088 AAF22032 AK097133 BAC04959 AL833653 CAH56229 AY598335 AAT06746 BC007123 BC010686 AAH10686 BC019909 AAH19909 BC112942 BC113656 AAI13657 BC143716 BP314109 CA441499 CB159561 CR749832 CAH18688 JF432508 ADZ15725 XM_011516994 XP_011515296 XM_011516995 XP_011515297 XM_011516996 XP_011515298 XR_928326 NM_014109 NP_054828 |
Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. {ECO:0000269|PubMed:17998543}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17998543}. |
Tissue Specificity | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. {ECO:0000269|PubMed:15721472, ECO:0000269|PubMed:17076897, ECO:0000269|PubMed:17660802}. |
Anti-ATAD2 antibody - ab68019 from Abcam
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Anti-ATAD2 antibody - ab118664 from Abcam
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Anti-ATAD2 antibody [CL0182] - ab154139 from Abcam
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Anti-ATAD2 antibody [EPR12730] - ab176319 from Abcam
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Anti-ATAD2 antibody [EPR12730] (Alexa Fluor® 647) - ab201353 from Abcam
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Anti-ATAD2 Antibody (aa203-232, AP) - LS-C232925 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232, FITC) - LS-C232927 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232, Biotin) - LS-C232926 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232, Azide-free, HRP) - LS-C249476 from LifeSpan Bioscience
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Anti-ATAD2 Antibody - LS-C306420 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232, PE) - LS-C232928 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232) - LS-C319649 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232) - LS-C156559 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa1205-1254) IHC-plus™ - LS-B9767 from LifeSpan Bioscience
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Anti-ATAD2 Antibody (aa203-232, APC) - LS-C232924 from LifeSpan Bioscience
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ATAD2 Antibody - NBP1-84123 from Novus Biologicals
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ATAD2 Antibody (CL0182) - NBP2-14786 from Novus Biologicals
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ATAD2 Antibody - H00029028-B01P from Novus Biologicals
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ATAD2 Antibody - NBP1-84122 from Novus Biologicals
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ATAD2 Polyclonal Antibody - bs-9110R from Bioss
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Anti-ATAD2 antibody produced in mouse - SAB1400512 from Sigma-Aldrich
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Anti-ATAD2 antibody produced in rabbit - HPA019860 from Sigma-Aldrich
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Monoclonal Anti-ATAD2 antibody produced in mouse - AMAB90541 from Sigma-Aldrich
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Anti-ATAD2 antibody produced in rabbit - HPA029424 from Sigma-Aldrich
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ATAD2 antibody - C-terminal region (ARP62208_P050) - ARP62208_P050 from Aviva Systems Biology
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