Gene Symbol | ATAD2 |
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Entrez Gene | 29028 |
Alt Symbol | ANCCA, CT137, PRO2000 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase family, AAA domain containing 2 |
Other Description | AAA nuclear coregulator cancer-associated protein|ATPase family AAA domain-containing protein 2 |
Swissprots | Q8N890 Q68CQ0 Q6PJV6 Q658P2 Q6PL18 Q9UHS5 Q14CR1 |
Accessions | EAW92033 EAW92034 EAW92035 EAW92036 Q6PL18 AF118088 AAF22032 AK097133 BAC04959 AL833653 CAH56229 AY598335 AAT06746 BC007123 BC010686 AAH10686 BC019909 AAH19909 BC112942 BC113656 AAI13657 BC143716 BP314109 CA441499 CB159561 CR749832 CAH18688 JF432508 ADZ15725 XM_011516994 XP_011515296 XM_011516995 XP_011515297 XM_011516996 XP_011515298 XR_928326 NM_014109 NP_054828 |
Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. {ECO:0000269|PubMed:17998543}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17998543}. |
Tissue Specificity | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. {ECO:0000269|PubMed:15721472, ECO:0000269|PubMed:17076897, ECO:0000269|PubMed:17660802}. |
Active human ATAD2 protein fragment - ab198131 from Abcam
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Human ATAD2 full length protein - ab153302 from Abcam
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Human ATAD2 protein fragment - ab198141 from Abcam
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ATAD2 Antibody Blocking Peptide - LS-E2162 from LifeSpan Bioscience
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ATAD2 Antibody Blocking Peptide - LS-E22725 from LifeSpan Bioscience
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ATAD2 Recombinant Protein - H00029028-P01 from Novus Biologicals
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ATAD2-Antibody-N-term-Blocking-peptide - BP13073a from Abgent, a WuXi AppTec company
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ATAD2 - H00029028-P01 from Acris Antibodies
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ATAD2 fusion protein - ag20947 from Proteintech Group
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Recombinant ATAD2 (981-1108) protein - 31376 from ActiveMotif
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Recombinant Human ATAD2, GST-tagged - ATAD2-11H from Creative Biomart
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Recombinant Human ASH1L, His&FLAG-tagged - ATAD2-31H from Creative Biomart
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Recombinant Human ATPase family AAA domain-containing protein 2(ATAD2) ,partial - CSB-YP747500HU CSB-EP747500HU CSB-BP747500HU CSB-MP747500HU from Cusabio
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ATAD2 Protein - abx165004 from Abbexa
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ATPase family AAA domain-containing protein 2(ATAD2) ,partial, Recombinant Protein - MBS1296068 from MyBioSource
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Recombinant Human ATAD2 protein, GST-tagged - ATAD2-51H from Creative Biomart
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ATAD2 Recombinant Protein Antigen - NBP1-84123PEP from Novus Biologicals
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ATAD2 Protein - NBP1-84122PEP from Novus Biologicals
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ATAD2 Peptide, Human - M34GP01074H from Creative Peptides
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ATAD2 peptide - orb374792 from Biorbyt
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