NCAPD2

Gene Symbol	NCAPD2
Entrez Gene	9918
Alt Symbol	CAP-D2, CNAP1, hCAP-D2
Species	Human
Gene Type	protein-coding
Description	non-SMC condensin I complex, subunit D2
Other Description	XCAP-D2 homolog|chromosome condensation related SMC associated protein 1|chromosome condensation-related SMC-associated protein 1|chromosome-associated protein D2|condensin complex subunit 1
Swissprots	Q8N6U3 Q15021 D3DUR4
Accessions	EAW88788 EAW88789 EAW88790 Q15021 AK022511 BAG51082 AK125155 BAC86066 AK128354 BAG54665 AK303310 BAG64379 AL548223 BC016913 AAH16913 BC028182 AAH28182 CN307514 D63880 BAA09930 DQ573571 NM_014865 NP_055680
Function	Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. {ECO:0000269|PubMed:11136719}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10958694}. Cytoplasm {ECO:0000269|PubMed:10958694}. Chromosome {ECO:0000269|PubMed:10958694}. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NCAPD2 Antibody Blocking Peptide - LS-E16853 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CNAP1 Protein - H00009918-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NCAPD2 Blocking Peptide - 33R-4246 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NCAPD2 - H00009918-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCAPD2 - H00009918-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCAPD2 fusion protein - ag4219 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Condensin complex subunit 1(NCAPD2) ,partial - CSB-YP618971HU CSB-EP618971HU CSB-BP618971HU CSB-MP618971HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CNAP1 Recombinant Protein Antigen - NBP1-88202PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CNAP1 Recombinant Protein Antigen - NBP1-88201PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NCAPD2 Antibody - SH-A13897 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

NCAPD2 Peptide, Human - M34GP10170H from Creative Peptides Category Peptide Source Synthetic. Species Human

Condensin complex subunit 1 (NCAPD2), partial, Recombinant Protein - MBS1448804 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human NCAPD2 Protein, GST-tagged - NCAPD2-1550H from Creative Biomart Category Protein Source Wheat Germ Species Human

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