E2F7

Gene Symbol	E2F7
Entrez Gene	144455
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	E2F transcription factor 7
Other Description	E2F-7|transcription factor E2F7
Swissprots	Q96AV8 B5MED9 B2RMR7 B3KUP8 A6NC74 B3KTZ5
Accessions	EAW97338 EAW97339 EAW97340 Q96AV8 AI380315 AK023043 AK096316 BAG53257 AK097677 BAG53510 BC016658 AAH16658 BC017481 BC136366 AAI36367 BC136367 AAI36368 DB159890 XM_011537966 XP_011536268 XM_011537967 XP_011536269 XM_011537968 XP_011536270 XM_011537969 XP_011536271 NM_203394 NP_976328
Function	Atypical E2F transcription factor that participates in various processes such as angiogenesis, polyploidization of specialized cells and DNA damage response. Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'- TTTC[CG]CGC-3'. Directly represses transcription of classical E2F transcription factors such as E2F1. Acts as a regulator of S-phase by recognizing and binding the E2-related site 5'-TTCCCGCC-3' and mediating repression of G1/S-regulated genes. Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3). Required for placental development by promoting polyploidization of trophoblast giant cells. Also involved in DNA damage response: up-regulated by p53/TP53 following genotoxic stress and acts as a downstream effector of p53/TP53-dep
Subcellular Location	Nucleus {ECO:0000269|PubMed:15133492}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human E2F7 protein fragment - ab153602 from Abcam Category Protein Source Wheat germ Species Human

E2F7 Antibody Blocking Peptide - LS-E3917 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

E2F7 Antibody Blocking Peptide - LS-E27031 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human E2F7 Protein - H00144455-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

E2F7-Antibody-Center-Blocking-Peptide - BP16112c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

E2F7 blocking peptide - GTX88444-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

E2f7 Blocking Peptide - 33R-5979 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

E2F7 Blocking Peptide - 33R-4945 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

E2F7 Peptide - AC21-1854-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

E2F7 - H00144455-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

E2F7 - H00144455-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

E2F7 Peptide - 46-982P from ProSci Category Peptide Species Human

E2F7 fusion protein - ag21599 from Proteintech Group Category Protein Source E. coli-derived, PET30a Species Human

Recombinant Human Transcription factor E2F7(E2F7) ,partial - CSB-YP846586HU CSB-EP846586HU CSB-BP846586HU CSB-MP846586HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

E2F7, Peptide - MBS426973 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog, Pig

E2F7 Peptide, Human - M34GP04670H from Creative Peptides Category Peptide Source Synthetic. Species Human

E2F7 Recombinant Protein Antigen - NBP2-57294PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Recombinant Human E2F7 Protein, GST-tagged - E2F7-3010H from Creative Biomart Category Protein Source Wheat Germ Species Human

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