Gene Symbol | MYRIP |
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Entrez Gene | 25924 |
Alt Symbol | SLAC2-C, SLAC2C |
Species | Human |
Gene Type | protein-coding |
Description | myosin VIIA and Rab interacting protein |
Other Description | Slp homologue lacking C2 domains|exophilin-8|myosin-VIIa- and Rab-interacting protein|rab effector MyRIP|slp homolog lacking C2 domains c|synaptotagmin-like protein homologue lacking C2 domains-c|synaptotagmin-like protein lacking C2 domains C |
Swissprots | Q9Y3V4 G3XAI8 Q32M42 Q32M41 B3KWM3 Q8IUF5 Q8NFW9 B7Z2H1 Q569F7 B3KWW4 B7Z9V3 |
Accessions | EAW64595 EAW64596 Q8NFW9 AB083783 BAC15555 AF396687 AAM43954 AK125334 BAG54185 AK126013 BAG54276 AK294714 BAH11857 AK310972 AK312412 AK316068 BAH14439 AL050090 CAB43262 BC092512 AAH92512 BC109311 AAI09312 BC109312 AAI09313 CF138044 DN999201 XM_011533575 XP_011531877 NM_001284423 NP_001271352 NM_001284424 NP_001271353 NM_001284425 NP_001271354 NM_001284426 NP_001271355 NM_015460 NP_056275 NR_104316 |
Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments (By similarity). {ECO:0000250}. |
Tissue Specificity | Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis. |
Slac2-c (H-100) - sc-135092 from Santa Cruz Biotechnology
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Slac2-c (K-17) - sc-66637 from Santa Cruz Biotechnology
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Slac2-c (N-18) - sc-66638 from Santa Cruz Biotechnology
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Anti-MYRIP antibody - ab113665 from Abcam
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Anti-MYRIP antibody - ab10149 from Abcam
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Anti-MYRIP antibody - ab130525 from Abcam
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Anti-MYRIP Antibody (aa659-686, FITC) - LS-C237878 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686, Biotin) - LS-C237879 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686, PE) - LS-C237880 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686, AP) - LS-C246554 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686, APC) - LS-C246555 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa658-686) - LS-C323214 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686, Azide-free, HRP) - LS-C248874 from LifeSpan Bioscience
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Anti-MYRIP Antibody (C-Terminus) - LS-C187231 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa659-686) - LS-C158350 from LifeSpan Bioscience
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Anti-MYRIP Antibody (aa846-859) IHC-plus⢠- LS-B4969 from LifeSpan Bioscience
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MYRIP Antibody - NBP1-84137 from Novus Biologicals
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MYRIP Antibody - NB100-1278 from Novus Biologicals
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MYRIP Antibody - H00025924-B01 from Novus Biologicals
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MYRIP Antibody - H00025924-B01P from Novus Biologicals
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MYRIP/SLAC2-C Polyclonal Antibody - bs-11038R from Bioss
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Rabbit Anti-MYRIP/SLAC2-C Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11038R-A350 from Bioss
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Rabbit Anti-MYRIP/SLAC2-C Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11038R-A488 from Bioss
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Rabbit Anti-MYRIP/SLAC2-C Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11038R-A555 from Bioss
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Rabbit Anti-MYRIP/SLAC2-C Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11038R-A647 from Bioss
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