Gene Symbol | MYRIP |
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Entrez Gene | 25924 |
Alt Symbol | SLAC2-C, SLAC2C |
Species | Human |
Gene Type | protein-coding |
Description | myosin VIIA and Rab interacting protein |
Other Description | Slp homologue lacking C2 domains|exophilin-8|myosin-VIIa- and Rab-interacting protein|rab effector MyRIP|slp homolog lacking C2 domains c|synaptotagmin-like protein homologue lacking C2 domains-c|synaptotagmin-like protein lacking C2 domains C |
Swissprots | Q9Y3V4 G3XAI8 Q32M42 Q32M41 B3KWM3 Q8IUF5 Q8NFW9 B7Z2H1 Q569F7 B3KWW4 B7Z9V3 |
Accessions | EAW64595 EAW64596 Q8NFW9 AB083783 BAC15555 AF396687 AAM43954 AK125334 BAG54185 AK126013 BAG54276 AK294714 BAH11857 AK310972 AK312412 AK316068 BAH14439 AL050090 CAB43262 BC092512 AAH92512 BC109311 AAI09312 BC109312 AAI09313 CF138044 DN999201 XM_011533575 XP_011531877 NM_001284423 NP_001271352 NM_001284424 NP_001271353 NM_001284425 NP_001271354 NM_001284426 NP_001271355 NM_015460 NP_056275 NR_104316 |
Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes. Colocalizes with actin filaments (By similarity). {ECO:0000250}. |
Tissue Specificity | Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis. |
Human MYRIP peptide - ab23187 from Abcam
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MYRIP Antibody Blocking Peptide - LS-E4789 from LifeSpan Bioscience
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MYRIP Antibody Blocking Peptide - LS-E25570 from LifeSpan Bioscience
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MYRIP Antibody Blocking Peptide - LS-E21747 from LifeSpan Bioscience
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MYRIP-Antibody-C-term-Blocking-Peptide - BP17165b from Abgent, a WuXi AppTec company
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MYRIP blocking peptide - GTX10149-PEP from GeneTex
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MYRIP Peptide - AC21-0399-P from Abcore
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MYRIP Peptide - 45-929P from ProSci
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Recombinant Human Rab effector MyRIP(MYRIP) ,partial - CSB-YP839876HU CSB-EP839876HU CSB-BP839876HU CSB-MP839876HU from Cusabio
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MYRIP (full length, N-term HIS tag) - TP760918 from Acris Antibodies
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MYRIP/SLAC2C, Peptide - MBS425935 from MyBioSource
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MYRIP Protein - NBP1-84137PEP from Novus Biologicals
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MYRIP Peptide, Human - M34GP10055H from Creative Peptides
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MYRIP fusion protein - Ag25558 from Proteintech Group
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Rab effector MyRIP (MYRIP), partial, Recombinant Protein - MBS1384531 from MyBioSource
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MYRIP Immunizing peptide - orb17083 from Biorbyt
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