Gene Symbol | ANP32E |
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Entrez Gene | 81611 |
Alt Symbol | LANP-L, LANPL |
Species | Human |
Gene Type | protein-coding |
Description | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
Other Description | LANP-like protein|acidic leucine-rich nuclear phosphoprotein 32 family member E|leucine-rich acidic nuclear protein like |
Swissprots | Q8WWW9 Q8N1S4 Q5TB20 B4E0I6 Q9BTT0 E9PEA6 Q5TB18 |
Accessions | CAI22806 CAI22807 CAI22808 CAI22809 EAW53575 EAW53576 EAW53577 EAW53578 EAW53579 Q9BTT0 AK025624 AK092672 BAC03942 AK095228 BAC04505 AK223469 BAD97189 AK303333 BAG64397 AK303392 BAG64448 AL832664 AL832674 AL833660 AM393076 CAL37954 AY057381 AAL25814 BC003380 AAH03380 BM974388 CB123292 DA379137 XM_005245513 XP_005245570 XM_005245514 XP_005245571 NM_001136478 NP_001129950 NM_001136479 NP_001129951 NM_001280559 NP_001267488 NM_001280560 NP_001267489 NM_030920 NP_112182 |
Function | Histone chaperone that specifically mediates the genome- wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. {ECO:0000269|PubMed:24463511}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. {ECO:0000269|PubMed:12438741}. |
LANPL (O-23) - sc-133723 from Santa Cruz Biotechnology
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LANPL (S-18) - sc-69301 from Santa Cruz Biotechnology
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Anti-LANPL antibody - ab5993 from Abcam
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Anti-LANPL antibody - ab84731 from Abcam
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Anti-LANPL antibody - ab191293 from Abcam
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Anti-LANPL antibody - ab115448 from Abcam
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Anti-PHAP III / ANP32E Antibody (aa21-44) - LS-C344600 from LifeSpan Bioscience
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Anti-PHAP III / ANP32E Antibody (C-Terminus) IHC-plus⢠- LS-B442 from LifeSpan Bioscience
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Anti-PHAP III / ANP32E Antibody (C-Terminus) - LS-C82977 from LifeSpan Bioscience
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Anti-PHAP III / ANP32E Antibody (aa151-200) - LS-C80882 from LifeSpan Bioscience
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LANPL Antibody - NBP1-56294 from Novus Biologicals
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LANPL Antibody - NBP1-77227 from Novus Biologicals
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LANPL Antibody - NBP1-03111 from Novus Biologicals
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LANPL Polyclonal Antibody - bs-6862R from Bioss
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Anti-ANP32E antibody produced in rabbit - AV46349 from Sigma-Aldrich
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Anti-ANP32E antibody produced in rabbit - SAB2100124 from Sigma-Aldrich
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Anti-ANP32E antibody produced in rabbit - SAB2900347 from Sigma-Aldrich
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Anti-PHAP III antibody produced in rabbit - PRS3147 from Sigma-Aldrich
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ANP32E antibody - middle region (ARP46349_P050) - ARP46349_P050 from Aviva Systems Biology
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ANP32E-Antibody-N-term - AP20559a from Abgent, a WuXi AppTec company
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ANP32E antibody - GTX85687 from GeneTex
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ANP32E Antibody - N-terminal region (OAAB18081) - OAAB18081 from Aviva Systems Biology
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Anti -LANP-L (Leucine-rich Acidic Nuclear Protein-like, Acidic Nuclear Phosphoprotein 32E,ANP32E) - L1238 from USBiological Life Science
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Anti -LANP-L (Leucine-rich Acidic Nuclear Protein-like, Acidic Nuclear Phosphoprotein 32E,ANP32E) - L1238-01 from USBiological Life Science
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LANPL antibody (FITC) - orb102896 from Biorbyt
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