| Gene Symbol |
SF3B6
|
| Entrez Gene |
51639
|
| Alt Symbol |
CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
splicing factor 3b, subunit 6, 14kDa
|
| Other Description |
SF3b 14 kDa subunit|pre mRNA branch site protein p14|pre-mRNA branch site protein p14|spliceosome-associated protein, 14 kDa subunit|spliceosome-associated protein, 14-kDa|splicing factor 3B subunit 6|splicing factor 3B, 14 kDa subunit
|
| Swissprots |
Q9Y3B4 Q53TM1
|
| Accessions |
AAY14664 EAX00767 Q9Y3B4 AF151868 AAD34105 AF161523 AAF29138 AF184213 AAG09698 AF401310 AAK94041 AK000621 AK311118 AK311908 BAG34849 BC015463 AAH15463 BG200650 JF432474 ADZ15691 NM_016047 NP_057131
|
| Function |
Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively. {ECO:0000269|PubMed:16432215}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Top Pathways |
Spliceosome
|