Gene Symbol | SF3B6 |
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Entrez Gene | 51639 |
Alt Symbol | CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a |
Species | Human |
Gene Type | protein-coding |
Description | splicing factor 3b, subunit 6, 14kDa |
Other Description | SF3b 14 kDa subunit|pre mRNA branch site protein p14|pre-mRNA branch site protein p14|spliceosome-associated protein, 14 kDa subunit|spliceosome-associated protein, 14-kDa|splicing factor 3B subunit 6|splicing factor 3B, 14 kDa subunit |
Swissprots | Q9Y3B4 Q53TM1 |
Accessions | AAY14664 EAX00767 Q9Y3B4 AF151868 AAD34105 AF161523 AAF29138 AF184213 AAG09698 AF401310 AAK94041 AK000621 AK311118 AK311908 BAG34849 BC015463 AAH15463 BG200650 JF432474 ADZ15691 NM_016047 NP_057131 |
Function | Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively. {ECO:0000269|PubMed:16432215}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Spliceosome |
Human SF3B14 full length protein - ab103908 from Abcam
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SF3B6 / SF3B14 Antibody Blocking Peptide - LS-E14654 from LifeSpan Bioscience
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SF3B6 / SF3B14 Antibody Blocking Peptide - LS-E14653 from LifeSpan Bioscience
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SF3B6 / SF3B14 Antibody Blocking Peptide - LS-E14922 from LifeSpan Bioscience
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SF3B6 / SF3B14 Antibody Blocking Peptide - LS-E14965 from LifeSpan Bioscience
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SF3B6 / SF3B14 Antibody Blocking Peptide - LS-E14966 from LifeSpan Bioscience
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SF3B14 Recombinant Protein - H00051639-P01 from Novus Biologicals
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Recombinant Human SF3B14 Protein - NBP1-50997 from Novus Biologicals
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SF3B14 Protein (OPPA00170) - OPPA00170 from Aviva Systems Biology
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Human SF3B14 protein - orb169282 from Biorbyt
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SF3B14 Blocking Peptide - 33R-5703 from Fitzgerald
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SF3B14 Blocking Peptide - 33R-3788 from Fitzgerald
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SF3B14 protein (His tag) - 80R-1678 from Fitzgerald
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SAP14 Blocking Peptide - abx063872 from Abbexa
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SF3B14 / SAP14 (1-125, His-tag) - AR09860PU-L from Acris Antibodies
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SF3B14 / SAP14 (1-125, His-tag) - AR09860PU-N from Acris Antibodies
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SF3B14 / SAP14 - H00051639-P01-02 from Acris Antibodies
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Splicing Factor 3B, 14 kDa Subunit, Human Recombinant - 228-12861-1 from RayBiotech
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Recombinant Human Splicing Factor 3B, 14 kDa Subunit - 228-12861-2 from RayBiotech
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Recombinant Human Splicing Factor 3B, 14 kDa Subunit - 228-12861-3 from RayBiotech
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SF3B14, 1-125aa, Human, His tag, E.coli - 01-P0920 from ARP American Research Products
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SF3B14 fusion protein - ag3045 from Proteintech Group
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SF3B14 Human - PRPS-112 from NeoScientific
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Recombinant Human SF3B14 Protein - BP002276-PRO-105 from Syd Labs
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SF3B14 Human Protein - GWB-BSP652 from Genway Biotech
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