Gene Symbol | SEMA3E |
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Entrez Gene | 9723 |
Alt Symbol | M-SEMAH, M-SemaK, SEMAH, coll-5 |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
Other Description | semaphorin-3E |
Swissprots | Q75M97 B4E1P1 Q75M94 O15041 |
Accessions | AAC69513 AAS07487 AAS07488 CAI84574 EAL24186 EAW76983 O15041 AB002329 BAA20789 AK297209 BAG59693 AK303925 BAG64853 BC140706 AAI40707 BC144338 AAI44339 BC152458 AAI52459 DA722912 DB215551 XM_011516715 XP_011515017 NM_001178129 NP_001171600 NM_012431 NP_036563 |
Function | Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down- regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Axon guidance |
SEMA3E (E-17) - sc-49734 from Santa Cruz Biotechnology
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SEMA3E (C-14) - sc-49733 from Santa Cruz Biotechnology
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SEMA3E (H-215) - sc-99142 from Santa Cruz Biotechnology
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SEMA3E (T-19) - sc-49736 from Santa Cruz Biotechnology
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Anti-Semaphorin 3E antibody - ab112886 from Abcam
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Anti-Semaphorin 3E antibody - ab128619 from Abcam
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Anti-Semaphorin 3E antibody [MM0900-21R12] - ab201656 from Abcam
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Anti-Semaphorin 3E antibody - C-terminal - ab80068 from Abcam
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Anti-SEMA3E / Semaphorin 3E Antibody - LS-C39036 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa387-400) - LS-C55444 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody - LS-C39037 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa25-775) - LS-C189833 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, AP) - LS-C282556 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, APC) - LS-C282557 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa25-775, clone 12K171, APC) - LS-C182945 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, Biotin) - LS-C282558 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, FITC) - LS-C282559 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, Azide-free, HRP) - LS-C282560 from LifeSpan Bioscience
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Anti-Semaphorin 3E / SEMA3E Antibody (C-Terminus, PE) - LS-C282562 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa593-642) - LS-C151722 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa581-669, Biotin) - LS-C297389 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa651-740, Biotin) - LS-C300364 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa651-740, FITC) - LS-C302300 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody - LS-C314117 from LifeSpan Bioscience
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Anti-SEMA3E / Semaphorin 3E Antibody (aa581-669, FITC) - LS-C304988 from LifeSpan Bioscience
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