Gene Symbol | SEMA3E |
---|---|
Entrez Gene | 9723 |
Alt Symbol | M-SEMAH, M-SemaK, SEMAH, coll-5 |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
Other Description | semaphorin-3E |
Swissprots | Q75M97 B4E1P1 Q75M94 O15041 |
Accessions | AAC69513 AAS07487 AAS07488 CAI84574 EAL24186 EAW76983 O15041 AB002329 BAA20789 AK297209 BAG59693 AK303925 BAG64853 BC140706 AAI40707 BC144338 AAI44339 BC152458 AAI52459 DA722912 DB215551 XM_011516715 XP_011515017 NM_001178129 NP_001171600 NM_012431 NP_036563 |
Function | Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down- regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Axon guidance |
Human Semaphorin 3E peptide - ab39320 from Abcam
|
||||||||||
SEMA3E / Semaphorin 3E Antibody Blocking Peptide - LS-E23501 from LifeSpan Bioscience
|
||||||||||
SEMA3E / Semaphorin 3E Antibody Blocking Peptide - LS-E26224 from LifeSpan Bioscience
|
||||||||||
SEMA3E / Semaphorin 3E Antibody Blocking Peptide - LS-E25836 from LifeSpan Bioscience
|
||||||||||
SEMA3E / Semaphorin 3E Blocking Peptide - LS-E9404 from LifeSpan Bioscience
|
||||||||||
Semaphorin 3E blocking peptide - GTX89609-PEP from GeneTex
|
||||||||||
Semaphorin 3E (internal) blocking peptide - GTX89180-PEP from GeneTex
|
||||||||||
Recombinant Human Semaphorin 3E, CF - 3239-S3-025 from R&D Systems
|
||||||||||
SEMA3E Immunizing peptide - orb17215 from Biorbyt
|
||||||||||
Semaphorin 3E Peptide - AC21-0668-P from Abcore
|
||||||||||
Semaphorin 3E Peptide - AC21-1055-P from Abcore
|
||||||||||
SEMA3E Peptide - 46-347P from ProSci
|
||||||||||
Semaphorin 3E Peptide - 46-348P from ProSci
|
||||||||||
SEMA3E fusion protein - Ag17126 from Proteintech Group
|
||||||||||
SEMA3E fusion protein - ag16290 from Proteintech Group
|
||||||||||
Recombinant Human SEMA3E, His-tagged - SEMA3E-2574H from Creative Biomart
|
||||||||||
Recombinant Human SEMA3E, His-tagged - SEMA3E-932H from Creative Biomart
|
||||||||||
Recombinant Semaphorin 3E (SEMA3E) - RPL920Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Semaphorin 3E (SEMA3E) - RPL920Mu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Semaphorin 3E (SEMA3E) - RPL920Mu02 from Uscn Life Science Inc.
|
||||||||||
Semaphorin 3E Blocking Peptide - CBP2418 from Cohesion Biosciences
|
||||||||||
SEMA3E Peptide - BS60460P from Bioworld Technology
|
||||||||||
Recombinant Semaphorin 3E (SEMA3E) - RPL920Hu01 from Cloud-clone
|
||||||||||
Recombinant Human Semaphorin-3E(SEMA3E) - CSB-YP020984HU CSB-EP020984HU CSB-BP020984HU CSB-MP020984HU from Cusabio
|
||||||||||
Recombinant Human Semaphorin 3E Protein, CF - 3239-S3 from R&D Systems
|