RECK

Gene Symbol	RECK
Entrez Gene	8434
Alt Symbol	ST15
Species	Human
Gene Type	protein-coding
Description	reversion-inducing-cysteine-rich protein with kazal motifs
Other Description	membrane-anchored glycoprotein (metastasis and invasion)|reversion-inducing cysteine-rich protein with Kazal motifs|suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs)|suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protein with kazal motifs)|suppressor of tumorigenicity 15 protein
Swissprots	O95980 Q8WX37 B2RNS1 Q5W0K6
Accessions	EAW58318 EAW58319 O95980 AK022897 AK292653 BAF85342 AK315073 BAG37543 BC032240 BC050306 BC060806 AAH60806 BC137093 AAI37094 BX648668 D50406 BAA34060 EF139848 JQ756320 XM_011518053 XP_011516355 NM_021111 NP_066934
Function	Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity	Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells.
Top Pathways	MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RECK full length protein - ab160023 from Abcam Category Protein Source Wheat germ Species Human

Human RECK protein fragment - ab160024 from Abcam Category Protein Source Wheat germ Species Human

RECK peptide - ab41252 from Abcam Category Peptide

RECK peptide - ab41253 from Abcam Category Peptide

RECK peptide - ab41254 from Abcam Category Peptide

RECK peptide - ab41255 from Abcam Category Peptide

RECK Antibody Blocking Peptide - LS-E21661 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RECK Antibody Blocking Peptide - LS-E10030 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RECK Protein - H00008434-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human RECK Protein - H00008434-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

RECK-Antibody-Center-Blocking-Peptide - BP9259c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Reck Blocking Peptide - 33R-8331 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RECK / ST15 - H00008434-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

RECK / ST15 - H00008434-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RECK / ST15 - H00008434-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RECK fusion protein - ag4955 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

RECK fusion protein - ag5448 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Reversion-inducing cysteine-rich protein with Kazal motifs(REC - CSB-YP019536HU CSB-EP019536HU CSB-BP019536HU CSB-MP019536HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RECK Protein - abx164233 from Abbexa Category Protein Species Human, Mouse, Rat

RECK Peptide, Human - M34GP13139H from Creative Peptides Category Peptide Source Synthetic. Species Human

RECK fusion protein - Ag25512 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

RECK Recombinant Protein Antigen - NBP2-57738PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Reversion-inducing cysteine-rich protein with Kazal motifs (RECK), partial, Recombinant Protein - MBS1037337 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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