CCNO

Gene Symbol CCNO
Entrez Gene 10309
Alt Symbol CCNU, CILD29, UDG2
Species Human
Gene Type protein-coding
Description cyclin O
Other Description cyclin U|cyclin domain containing|cyclin-O
Swissprots Q0P6J2 A8K1W5 Q9H6B0 P22674 Q9UMD5
Accessions AAB05817 EAW54912 EAW54913 P22674 AK026075 BAB15351 AK290030 BAF82719 BC004877 AAH04877 BC017345 BC056254 BC143905 BC143907 BC160041 AAI60041 BI832060 BX096363 HY011414 X52486 CAA36728 NM_021147 NP_066970 NR_125346 NR_125347 NR_125348 NM_001024592
Function Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. {ECO:0000269|PubMed:24747639}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:24747639}. Note=Localizes to the apical part of cytoplasm. {ECO:0000269|PubMed:24747639}.
Tissue Specificity Present in respiratory cells (at protein level). {ECO:0000269|PubMed:24747639}.

cyclin O (F-14) - sc-82066 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

cyclin O (F-3) - sc-374633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UDG2 (F-3): sc-374633. Western blot analysis of UDG2 expression in non-transfected: sc-117752 (A) and human UDG2 transfected: sc-173001 (B) 293T whole cell lysates.

cyclin O (H-267) - sc-68886 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cyclin O (H-267): sc-68886. Western blot analysis of cyclin O expression in non-transfected: sc-117752 (A) and human cyclin O transfected: sc-173001 (B) 293T whole cell lysates.

cyclin O (P-19) - sc-82068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CCNO antibody - ab47682 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab47682 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab47682, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CCNO antibody - ab47681 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30, AP) - LS-C253769 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30, Biotin) - LS-C253771 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30, FITC) - LS-C253772 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30, APC) - LS-C253770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30, Azide-free, HRP) - LS-C253773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (N-Terminus) - LS-C151778 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CCNO / UNG2 antibody Western Blot of Fetal Heart.

Anti-CCNO / UNG2 Antibody (Internal) - LS-C19613 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Cyclin O in human bladder tissue lysate with Cyclin O antibody at (A) 1 and (B) 2 ug/ml.

Anti-CCNO / UNG2 Antibody (aa1-30, PE) - LS-C253774 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody (aa1-30) - LS-C320128 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCNO / UNG2 Antibody IHC-plus™ - LS-B7280 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCNO / Cyclin O antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7280 concentration 5 ug/ml.

Anti-CCNO / UNG2 Antibody (aa1-30) - LS-C168483 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CCNO Antibody western blot of 293 cell line lysates (35 ug/lane). The CCNO antibody detected the CCNO protein (arrow).

Anti-CCNO / UNG2 Antibody (N-Terminus) IHC-plus™ - LS-B616 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCNO / Cyclin O antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B616 concentration 5 ug/ml.

Cyclin-O Antibody - NBP2-14806 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Cyclin-O Antibody [NBP2-14806] - Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Cyclin-O Antibody - NBP1-98285 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 50 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cyclin-O Antibody [NBP1-98285] - Titration: 1.0 ug/ml Positive Control: Fetal Heart.

Cyclin-O Antibody - H00010309-B01P-50ug from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-UNG2 (ab1) antibody produced in rabbit - PRS3859 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UNG2: <B>Cat. No. PRS3859</B> Western blot analysis of UNG2 in mouse bladder tissue lysate with UNG2 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.

Anti-CCNO antibody produced in rabbit - HPA050090 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CCNO:<B>Cat. No. HPA050090</B>: Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Anti-UNG2 (ab2) antibody produced in rabbit - PRS3861 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-UNG2: <B>Cat. No. PRS3861</B> Western blot analysis of UNG2 in human bladder tissue lysate with UNG2 antibody at (A) 1 and (B) 2 μg/mL.

Anti-CCNO/UNG2 antibody produced in rabbit - SAB2900399 from Sigma-Aldrich

Prices $464.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CCNO/UNG2: <B>Cat. No.SAB2900399</B>: Skin: Formalin-Fixed Paraffin-Embedded (FFPE).
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