Gene Symbol |
CCNO
|
Entrez Gene |
10309
|
Alt Symbol |
CCNU, CILD29, UDG2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cyclin O
|
Other Description |
cyclin U|cyclin domain containing|cyclin-O
|
Swissprots |
Q0P6J2 A8K1W5 Q9H6B0 P22674 Q9UMD5
|
Accessions |
AAB05817 EAW54912 EAW54913 P22674 AK026075 BAB15351 AK290030 BAF82719 BC004877 AAH04877 BC017345 BC056254 BC143905 BC143907 BC160041 AAI60041 BI832060 BX096363 HY011414 X52486 CAA36728 NM_021147 NP_066970 NR_125346 NR_125347 NR_125348 NM_001024592
|
Function |
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. {ECO:0000269|PubMed:24747639}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:24747639}. Note=Localizes to the apical part of cytoplasm. {ECO:0000269|PubMed:24747639}.
|
Tissue Specificity |
Present in respiratory cells (at protein level). {ECO:0000269|PubMed:24747639}.
|