ZCCHC11

Gene Symbol ZCCHC11
Entrez Gene 23318
Alt Symbol PAPD3, TUT4
Species Human
Gene Type protein-coding
Description zinc finger, CCHC domain containing 11
Other Description PAP associated domain containing 3|TUTase 4|terminal uridylyltransferase 4|zinc finger CCHC domain-containing protein 11
Swissprots Q12764 B7Z8J5 A2RRP0 Q5TAX3 Q86XZ3 Q5TAX2 Q5TAX4 D3DQ35
Accessions EAX06778 EAX06780 Q5TAX3 AK025698 AK095733 AK124868 AK307579 AK308427 BC012047 BC018753 BC035820 BC048301 BC131734 AAI31735 BX439159 BX648248 BX648783 BX649065 D83776 BAA12105 DA748708 R60512 XM_005270676 XP_005270733 XM_005270678 XP_005270735 XM_005270679 XP_005270736 XM_005270680 XP_005270737 XM_005270681 XP_005270738 XM_005270682 XP_005270739 XM_005270683 XP_005270740 XM_005270684 XP_005270741 XM_005270685 XP_005270742 XM_006710498 XP_006710561 XM_006710499 XP_006710562 XM_006710500 XP_006710563 XM_011541097 XP_011539399 XM_011541098 XP_011539400 XM_011541099 XP_011539401 XM_011541100 XP_011539402 XM_011541101 XP_011539403 XM_011541102 XP_011539404 NM_001009882 NM_001009881 NP_001009881 NM_015269 NP_056084
Function Uridylyltransferase that acts as a suppressor of microRNA (miRNA) biogenesis by specifically mediating the terminal uridylation of some miRNAs. Catalyzes the 3' uridylation of precursor let-7 (pre-let-7), a miRNA precursor. Uridylated pre- let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cells and is required for ES cells to maintain pluripotency. Does not bind RNA by itself, recruited to pre-let-7 miRNAs via its interaction with LIN28A and LIN28B. Also catalyzes the 3' uridylation of miR-26A, a miRNA that represses IL6 transcript, leading to abrogate IL6 transcript repression and promote cytokine expression. May also suppress Toll-like receptor-induced NF-kappa-B activity via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation. {ECO:0000269|PubMed:16643855, ECO:0000269|PubMed:19703396}.
Subcellular Location Nucleus. Cytoplasm. Note=Translocates into the cytoplasm following treatment of the cell with LPS.

Anti-ZCH11 antibody - ab89165 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-ZCH11 antibody (ab89165) at 1 µg/ml + Human spleen tissue lysate at 50 µg

Anti-ZCH11 antibody - ab128180 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab128180, at 1/250 dilution, labelling ZCH11 in formalin-fixed, paraffin-embedded Human prostate carcinoma tissue by immunohistochemistry followed by DAB staining.

Anti-ZCH11 antibody - ab118917 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZCH11 antibody (ab118917) at 1 µg/ml + ACHN cell lysate at 10 µg

Anti-ZCH11 antibody - ab9940 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab9940 staining ZCH11 in Human Lymph Node at 4 µg/ml. Steamed antigen retrieval with citrate buffer pH 6 was performed, antibody revealed with HRP-staining

Anti-ZCH11 antibody - C-terminal - ab201226 from Abcam

Prices $359.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human lymph node tissue labeling ZCH11 with ab201226 at 1/100 dilution.

Anti-KIAA0191 / ZCCHC11 Antibody (aa1568-1600) - LS-C344648 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from mouse spleen, mouse thymus tissue lysate (from left to right) with Zcchc11 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-KIAA0191 / ZCCHC11 Antibody (aa1631-1644) - LS-C55702 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-KIAA0191 / ZCCHC11 Antibody (aa1-50) - LS-C286131 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ZCCHC11 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-ZCCHC11 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-KIAA0191 / ZCCHC11 Antibody (aa1403-1452) IHC-plus™ - LS-B8244 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIAA0191 / ZCCHC11 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8244 dilution 5-7.5 ug/ml.

Anti-KIAA0191 / ZCCHC11 Antibody - LS-C335618 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ZCCHC11 antibody.

Anti-KIAA0191 / ZCCHC11 Antibody (aa830-844) - LS-C154880 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ZCCHC11 antibody (0.2 ug/ml) staining of different Testis lysates from wild type 8-9 week old C57BL/6 (wt) and knock-out (KO) mice (35 ug protein in RIPA buffer). Primary incubation was 2 hours. Detected by chemiluminescence. Data obtained from an anonymous customer.

Anti-KIAA0191 / ZCCHC11 Antibody (aa250-300) - LS-C289359 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ZCCHC11 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-ZCCHC11 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-KIAA0191 / ZCCHC11 Antibody (aa250-300) - LS-C286934 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse ZCCHC11 by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-ZCCHC11 used at a dilution of 1:250.

ZCCHC11/TUT4 Antibody - NBP1-83027 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZCCHC11/TUT4 Antibody [NBP1-83027] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

ZCCHC11/TUT4 Antibody - NBP1-83026 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZCCHC11/TUT4 Antibody [NBP1-83026] - Staining of human cell line U-2 OS shows positivity in nucleoli.

ZCCHC11/TUT4 Antibody - NB100-783 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: ZCCHC11/TUT4 Antibody [NB100-783] - (4 ug/ml) staining of paraffin embedded Human Lymph Node. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

ZCCHC11/TUT4 Antibody - H00023318-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ZCCHC11/TUT4 Antibody [H00023318-B01P] - Analysis of ZCCHC11 expression in human spleen.

ZCCHC11/TUT4 Antibody - NBP1-42654 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZCCHC11/TUT4 Antibody [NBP1-42654] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at 0.04 ug/ml.

ZCCHC11/TUT4 Antibody - H00023318-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ZCCHC11/TUT4 Antibody [H00023318-D01P] - Analysis of ZCCHC11 expression in transfected 293T cell line by ZCCHC11 polyclonal antibody.Lane 1: ZCCHC11 transfected lysate(34.10 KDa).Lane 2: Non-transfected lysate.

Anti-ZCCHC11 antibody produced in rabbit - SAB1410417 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZCCHC11: <B>Cat. No. SAB1410417</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~34.1 kDa using ZCCHC11 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ZCCHC11 antibody produced in rabbit - HPA027973 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZCCHC11: <B>Cat. No. HPA027973</B>: Immunohistochemical staining of human smooth muscle shows distinct cytoplasmic positivity.

Anti-ZCCHC11 antibody produced in rabbit - SAB2106202 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZCCHC11: <B>Cat. No. SAB2106202</B>: ZCCHC11 in ACHN cell lysates with ZCCHC11 antibody at 1.0 μg/mL.

Anti-ZCCHC11 (C-terminal) antibody produced in goat - SAB2501506 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZCCHC11 (C-terminal) <B>Cat. No. SAB2501506</B>: (4 μg/mL) staining of paraffin embedded Human Lymph Node. Steamed Antigen retrieval with citrate buffer (pH 6), HRP-staining.

Anti-ZCCHC11 antibody produced in rabbit - HPA027412 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZCCHC11: <B>Cat. No. HPA027412</B>: Immunohistochemical staining of human smooth muscle shows distinct cytoplasmic positivity.

Anti-ZCCHC11 antibody produced in mouse - SAB1400453 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-ZCCHC11, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400453</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~185.2 kDa using human spleen lysate.
Search more